Is it contagious if my partner has the "big three positives"?

Mar 17, 2025 Source: Cainiu Health

Dr. Shen Yonghua

Introduction

"Big Three Positive" of hepatitis B is caused by infection with the hepatitis B virus and is contagious. It may spread through routes such as blood, mother-to-child transmission, and sexual contact. Generally, when the virus is active, the probability of transmission may increase. To reduce the risk of infection, it is recommended to receive the vaccine in a timely manner and maintain a safe distance from infected individuals.

In general, "Big Three Positive" (commonly known as HBeAg-positive chronic hepatitis B) refers to a positive result for three specific markers in the hepatitis B virus (HBV) blood test, indicating infection with HBV. Patients with "Big Three Positive" typically are contagious. If symptoms of hepatitis B "Big Three Positive" appear, prompt medical attention is recommended. Detailed analysis is as follows:

"Big Three Positive" refers to a test result showing positivity for hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), and hepatitis B core antibody (anti-HBc) in the five-item hepatitis B test. This indicates that the hepatitis B virus in the patient's body is relatively active and may be in a state of replication. Hepatitis B "Big Three Positive" is an infectious disease that may be transmitted through blood, mother-to-child transmission, or sexual contact. The higher the viral load, the greater the risk of transmission may be.

To reduce the risk of developing hepatitis B, it is recommended to follow a doctor's guidance and receive the hepatitis B vaccine timely to enhance individual immunity. Additionally, it is important to maintain a certain distance from infected individuals and avoid close contact or sharing needles, syringes, toothbrushes, and other personal items with them.

If there is a patient with hepatitis B "Big Three Positive" at home, regular observation is necessary. When symptoms such as nausea, poor appetite, or yellowish complexion appear, timely medical examination is needed, and treatment should be guided by a doctor after diagnosis to avoid delaying the condition.

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Can Lanxin Kushen Tablets treat HBeAg-positive chronic hepatitis B?

Kushenin tablets (Kushen tablets) refer to tablets containing oxymatrine. "Big Three Positive" (commonly known as "Da San Yang") indicates a condition in which the hepatitis B surface antigen, hepatitis B e-antigen, and hepatitis B core antibody all test positive during the hepatitis B five-panel test. Oxymatrine tablets can be used in the treatment of "Big Three Positive." Patients should normally avoid consuming irritating foods, such as spicy or greasy foods, and should eat more liver-friendly foods, such as vegetables, fruits, and legumes, to help protect liver health.

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What should patients with "Big Three Yang" pay attention to in their diet?

Generally, "Big Three Positive" refers to a condition where, in the five-item hepatitis B test, the hepatitis B surface antigen, hepatitis B e-antigen, and hepatitis B core antibody all show positive results. Patients should pay attention to maintaining a balanced diet, controlling fat intake, consuming adequate amounts of high-quality protein, increasing intake of vitamins and minerals, and strictly abstaining from alcohol. Regular liver function tests and quantitative hepatitis B virus tests should also be performed routinely.

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Can mothers with "Big Three Yang" (positive for HBsAg, HBeAg, and HBcAb) breastfeed their babies?

"Big Three Positive" refers to a situation in the five-item hepatitis B test where the hepatitis B surface antigen, hepatitis B e antigen, and hepatitis B core antibody are all positive. Whether a mother who is "Big Three Positive" can breastfeed her baby needs to be determined based on the viral load of hepatitis B virus in her body. If the hepatitis B viral load is low, breastfeeding may be possible; however, if the viral load is high, breastfeeding is generally not recommended.

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What does an MRI examination for "Big Three Positive" involve?

MRI for "Big Three Yang" is usually used to examine space-occupying lesions in the liver. "Big Three Yang" is a type of hepatitis B, and also a bacterial infectious disease primarily caused by infection with the "Big Three Yang" bacteria. Besides infection, it is also closely related to an individual's immune system and poor daily habits. Hepatitis B virus infection triggers the body's overall immune response, leading to the production of various serum immunological markers.

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Does the husband being "big three positive" (positive for HBsAg, HBeAg, and HBV DNA) affect the fetus if the wife is pregnant?

Hepatitis B is an infectious disease caused by the hepatitis B virus, which can be transmitted to others through blood, sexual contact, mother-to-child transmission, and other routes. "Big three positive" (commonly known as "big three yang") refers to a specific pattern of hepatitis B markers. If the husband has the "big three positive" status and the wife becomes pregnant after he develops the infection, it may affect the fetus; otherwise, there is no impact. After pregnancy, the wife should undergo monitoring and treatment for hepatitis B virus under the guidance of a physician.

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Can the "Big Three Yang" virus be cured effectively?

In general, whether "big three positive" (a term referring to positive results for HBsAg, HBeAg, and anti-HBc) with high viral load can be cured mainly depends on the acute or chronic nature of the disease and the patient's immune system status. If the patient has acute hepatitis B, the immune system is usually able to respond more effectively to the virus, and the condition generally can be cured. However, for patients with chronic hepatitis, whose immune system has already been compromised, it may be difficult to achieve a complete cure.

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Can patients with "Big Three Yang" take Cornus officinalis (Shanzhuyu)?

If a patient with "Big Three Yang" (positive for HBsAg, HBeAg, and HBcAb) has normal liver function, no significant liver inflammation or activity, and no other severe complications, moderate consumption of Cornus officinalis (Shanzhuyu) may not cause notable adverse effects. Under the guidance of a physician, Cornus officinalis might be used as part of adjunctive therapy, especially for improving symptoms related to liver and kidney conditions. When considering the use of any herbal remedy,

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Can someone with "Big Three Yang" take Rehmannia glutinosa (prepared)?

When patients with "Big Three Yang" (Da San Yang) develop symptoms of liver and kidney yin deficiency, such as dry mouth and throat, soreness and weakness in the lower back and knees, dizziness, and tinnitus, the nourishing-yin and kidney-tonifying effects of Rehmannia glutinosa (Shu Di Huang) can help alleviate these discomforts. Appropriate consumption of Shu Di Huang at this time may help improve the yin-deficient condition and provide certain supportive benefits for recovery. However, it is not recommended for individuals with excessive internal damp-heat or those with spleen and stomach deficiency.

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