Can taking metformin help with weight loss?
Mar 17, 2025
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, metformin is available in various dosage forms including tablets and capsules. Metformin has a certain weight-reduction effect, but it is not recommended for weight loss. Metformin is an oral hypoglycemic agent primarily used to treat type 2 diabetes. It effectively lowers blood glucose levels by inhibiting hepatic glycogen output and increasing insulin sensitivity in peripheral tissues.
Generally, metformin is available in various dosage forms, including tablets and capsules. Metformin has certain weight-loss effects; however, it is not recommended for weight loss purposes. Detailed analysis is as follows:
Metformin is an oral hypoglycemic medication primarily used in the treatment of type 2 diabetes. It effectively lowers blood glucose levels by inhibiting hepatic glucose production and increasing insulin sensitivity in peripheral tissues. However, besides its glucose-lowering effects, metformin may cause gastrointestinal irritation, potentially leading to adverse symptoms such as nausea, vomiting, and diarrhea. These side effects can suppress appetite and reduce food intake to some extent, thus contributing to weight loss. Although metformin has certain weight-loss benefits, it is not recommended solely for weight reduction, as long-term use might increase the burden on the gastrointestinal system. Therefore, using metformin for weight loss poses considerable risks for individuals without diabetes.
Weight loss should be achieved through a healthy lifestyle, including balanced nutrition and regular physical activity, rather than relying on medications.
