What are the side effects of Marvelon?
Mar 19, 2025
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, Marvelon usually refers to Desogestrel and Ethinylestradiol Tablets, a short-acting oral contraceptive. Its possible side effects include weight gain, mood changes, skin problems, elevated blood pressure, and abnormal liver function. As a commonly used short-acting contraceptive, Desogestrel and Ethinylestradiol Tablets have the effects of contraception and menstrual regulation, but they may also cause various side effects during use.
Generally speaking, Marvelon refers to desogestrel and ethinyl estradiol tablets. Possible side effects may include weight gain, mood changes, skin problems, elevated blood pressure, and abnormal liver function. A detailed analysis is as follows:
1. Weight gain
Hormonal components in the medication can affect water and sodium metabolism as well as fat metabolism in the body, leading to fluid retention and fat accumulation. Some women may experience weight gain as a result.
2. Mood changes
During the use of desogestrel and ethinyl estradiol tablets, mood fluctuations such as depression, anxiety, irritability, and anger may occur. This is related to the medication's regulation of hormone levels in the body, which affects the balance of neurotransmitters and thereby influences emotional states.
3. Skin problems
The hormones in desogestestrel and ethinyl estradiol tablets can alter the endocrine environment of the skin, interfere with normal oil secretion and metabolic pathways, and disrupt the skin's original state of balance. They may also stimulate melanocytes to become overactive, promoting increased melanin synthesis and deposition, which can result in skin pigmentation issues such as melasma on the face.
4. Elevated blood pressure
The hormonal components in desogestrel and ethinyl estradiol tablets can affect the balance of the renin-angiotensin-aldosterone system, leading to water and sodium retention and increased blood volume. At the same time, the hormones may alter the sensitivity of blood vessel walls, causing vasoconstriction and increased peripheral vascular resistance. The increase in blood pressure is more pronounced in women with a family history of hypertension or risk factors for cardiovascular disease.
5. Abnormal liver function
After entering the body, desogestrel and ethinyl estradiol tablets are mainly metabolized by the liver. Long-term use keeps the liver in a state of high workload. Liver cells may suffer some degree of damage, leading to abnormal liver function indicators, such as elevated liver enzymes.
As a commonly used short-term contraceptive, desogestrel and ethinyl estradiol tablets have the functions of contraception and menstrual regulation; however, various side effects may also occur during use. Therefore, careful selection is necessary when using these pills, and close attention should be paid to changes in physical condition.
