What category of medication does Rotundine belong to?

Mar 20, 2025 Source: Cainiu Health

Dr. Yang Ziqi

Introduction

Rotundine is a non-narcotic analgesic with analgesic, sedative, hypnotic, and tranquilizing effects. Its analgesic effect is weaker than that of pethidine but stronger than that of ordinary antipyretic analgesics. At therapeutic doses, rotundine does not cause respiratory depression or gastrointestinal smooth muscle spasm, and it shows better efficacy for chronic persistent pain and visceral dull pain.

Generally speaking, Rotundine belongs to the category of analgesic drugs and is commonly available in tablet and injection forms. Detailed analysis is as follows:

Rotundine is a non-narcotic analgesic with analgesic, sedative, hypnotic, and tranquilizing effects. Its analgesic effect is weaker than that of pethidine but stronger than that of common antipyretic analgesics. At therapeutic doses, Rotundine does not cause respiratory depression or gastrointestinal smooth muscle spasm. It is effective for chronic persistent pain and visceral dull pain, but less effective for acute sharp pain, such as postoperative pain, traumatic pain, and advanced cancer pain.

The mechanism of action of Rotundine may be related to the inhibition of the ascending activating system of the brainstem reticular structure and blocking the function of dopamine receptors in the brain. It is commonly used to treat pain caused by gastric and duodenal ulcers, dysmenorrhea, postpartum uterine contraction pain, tension insomnia, and spasmodic cough. However, while producing analgesic effects, Rotundine may also cause sedation and drowsiness. Therefore, it should be used under the guidance of a physician, and driving, working at heights, and operating precision instruments should be avoided during treatment.

The dosage and administration of Rotundine should be determined according to specific indications and medical advice. Additionally, possible adverse reactions and precautions should be noted during use to ensure the safety and efficacy of the medication.

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