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What are the functions and effects of Intravenous Human Immunoglobulin (pH4)?

Mar 24, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Intravenous Human Immunoglobulin (pH4) is a mixture of antibodies extracted from the plasma of a large number of healthy individuals, primarily used for the treatment of immune system-related diseases. It generally has anti-inflammatory effects, serves as replacement therapy, provides passive immune protection, prevents and treats specific viral diseases, and enhances immune function.

Intravenous human immunoglobulin (pH4) is a mixture of antibodies extracted from the plasma of numerous healthy individuals, primarily used for the treatment of immune system-related diseases. It generally has functions and effects such as anti-inflammatory action, replacement therapy, providing passive immune protection, prevention and treatment of specific viral diseases, and enhancing immune function. A detailed analysis is as follows:

1. Anti-inflammatory Action

Intravenous human immunoglobulin (pH4) has certain anti-inflammatory properties. It contains abundant antibodies that can neutralize inflammatory mediators in the body, inhibit excessive activation of inflammatory responses, thereby alleviating inflammatory symptoms and tissue damage. It can be used in the treatment of certain autoimmune diseases and neurological inflammations.

2. Replacement Therapy

Patients with immunodeficiency disorders, such as primary immunoglobulin deficiency or secondary immunoglobulin deficiency, may use intravenous human immunoglobulin (pH4) as replacement therapy under medical guidance. By supplementing the immunoglobulins lacking in the patient's body, it helps establish an effective immune defense mechanism, preventing infections and disease occurrence.

3. Providing Passive Immune Protection

For patients with weakened immune function, such as those with immunodeficiency diseases or cancer patients undergoing chemotherapy or radiotherapy, intravenous human immunoglobulin (pH4) can provide short-term passive immune protection. This helps reduce the risk of infections and assists patients through periods of immunosuppression.

4. Prevention and Treatment of Specific Viral Diseases

This medication can be used for the prevention and treatment of specific viral diseases, such as hepatitis B, chickenpox, and shingles. By providing specific antibodies, intravenous human immunoglobulin (pH4) helps the body resist infection from these viruses, alleviates disease severity, and promotes recovery.

5. Enhancing Immune Function

Intravenous human immunoglobulin (pH4) contains a broad range of antibodies that can recognize and bind to various pathogens, thereby enhancing the body's immune response to pathogens and improving overall immunity.

In some emergency situations, such as severe infections or life-threatening immune-mediated conditions, intravenous human immunoglobulin (pH4) can serve as a rapid and effective treatment option to help control the condition and buy time for further treatment.

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