What medications are used for mouth ulcers?
Jun 05, 2025
Source: Cainiu Health
Dr. Liu Chao
Introduction
For oral ulcers, medications such as watermelon frost, chlorhexidine mouthwash, recombinant human epidermal growth factor gel, dexamethasone acetate adhesive tablets, and vitamin B2 tablets may be used. It is recommended to follow medical advice regarding medication use. Good oral hygiene should be maintained during treatment, and spicy or irritating foods should be avoided. Adequate sleep and nutrition are also important. If ulcers persist for more than two weeks without healing or are accompanied by other systemic symptoms, prompt medical consultation is recommended.
Generally, oral ulcers can be treated with medications such as watermelon frost, chlorhexidine mouthwash, recombinant human epidermal growth factor gel, dexamethasone acetate adhesive tablets, and vitamin B2 tablets. It is recommended to follow medical advice regarding medication use. Detailed explanations are as follows:
1. Watermelon Frost
Mainly contains watermelon frost and borneol, with effects of clearing heat, detoxifying, reducing swelling, and relieving pain. It can be applied directly to the ulcerated area to alleviate pain and promote healing. Suitable for mild oral ulcers, especially those caused by excessive internal heat accompanied by localized redness and pain.
2. Chlorhexidine Mouthwash
Main ingredient is chlorhexidine gluconate, an antimicrobial disinfectant that inhibits bacterial growth in the mouth, prevents secondary infection of ulcers, and creates a clean environment for wound healing. Suitable for patients with large ulcer surfaces or signs of infection, such as local redness, swelling, or purulent discharge.
3. Recombinant Human Epidermal Growth Factor Gel
Contains recombinant human epidermal growth factor, which promotes the proliferation and differentiation of oral mucosal epithelial cells, accelerates ulcer healing, and reduces scar formation. Suitable for recurrent, refractory ulcers or wounds that heal slowly.
4. Dexamethasone Acetate Adhesive Tablets
Contain dexamethasone, which has anti-inflammatory and antiallergic effects, reducing local inflammatory response and relieving pain and swelling. Suitable for moderate to severe oral ulcers, such as those with larger diameters and intense pain; short-term use can rapidly control symptoms.
5. Vitamin B2 Tablets
Supplementing vitamin B2 helps with energy metabolism and mucosal repair. A deficiency in vitamin B2 may lead to recurrent oral ulcers. Suitable for ulcers caused by vitamin deficiency or as an adjunctive therapy to improve overall mucosal condition.
Good oral hygiene should be maintained during treatment, with avoidance of spicy and irritating foods. Adequate sleep and nutrition should also be ensured. If ulcers persist for more than two weeks without healing or are accompanied by other systemic symptoms, the possibility of malignancy should be considered, and prompt medical consultation is recommended.
