How long does pain last after chemotherapy?

Pain caused by chemotherapy usually gradually subsides within 10 to 15 days. If significant discomfort persists beyond two weeks, prompt medical evaluation is recommended.

Chemotherapy is a core treatment for various malignant tumors. Its cytotoxic effects can markedly shrink tumor masses, but it may also damage normal tissues. Areas with rapidly proliferating cells—such as bone marrow, mucous membranes, and nerve endings—are most vulnerable, leading to side effects such as pain, nausea, and hair loss. The severity of pain is closely related to the type of drug, cumulative dose, and individual tolerance; regimens involving platinum agents or paclitaxel are more likely to induce peripheral neuropathy.

Pain management can focus on three aspects: medication, physical interventions, and lifestyle adjustments. Mild pain can be managed under medical guidance with nonsteroidal anti-inflammatory drugs (NSAIDs) or neuroregulators such as gabapentin. Local heat application and gentle massage may relieve muscle tension, but should avoid puncture sites and areas with skin damage. If pain interferes with sleep or presents as burning or electric shock-like sensations, neuropathic pain should be suspected, warranting timely escalation of analgesic therapy.

During chemotherapy, maintaining approximately 2000 mL of fluid intake daily—consumed in small amounts throughout the day—helps accelerate drug elimination and reduces urinary system toxicity. Diet should follow the principles of "light, low-fat, high-protein" intake, using a strategy of small, frequent meals, with each meal reaching about 70% fullness. Avoid alternating hot and cold foods, as well as hard or spicy items, to minimize risks of oral mucositis and vomiting. Remaining seated or walking slowly for 30 minutes after meals helps prevent reflux, avoiding immediate recumbency.

As treatment progresses, toxicities may accumulate. Patients are advised to collaborate with oncologists, pain specialists, and nutritionists before starting therapy to develop an individualized side effect monitoring plan. Dynamically recording pain scores, food intake, and urination patterns enables timely adjustment of supportive care strategies.