What is the storage temperature for insulin?

Jul 08, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, the storage temperature of insulin should be distinguished based on whether it has been opened, to ensure its stability and effectiveness. To avoid insulin失效 (losing effectiveness) and affecting treatment outcomes, it is recommended to strictly follow the product instructions for storage and use it under medical guidance. Additionally, insulin should be kept in its original packaging, protected from moisture and light, and inspected regularly for appearance.

Generally, the storage temperature of insulin should be determined based on whether it is opened or unopened to ensure its stability and effectiveness. The details are as follows:

Unopened insulin should be stored in the refrigerator at a temperature between 2℃ and 8℃ to ensure its efficacy and safety. It should be placed in the middle shelf of the refrigerator, away from areas with significant temperature fluctuations such as the freezer compartment and the refrigerator door, to prevent freezing due to excessively low temperatures or accelerated degradation due to high temperatures.

Once opened or in use, insulin can be stored at room temperature but should not exceed 28 days. It must be protected from direct sunlight and high-temperature environments. If the room temperature exceeds this range, the insulin should be returned to the refrigerator for storage. In high-temperature environments, it is recommended to store insulin in an insulated bag to reduce the impact of temperature fluctuations on its stability.

To avoid reduced effectiveness of insulin affecting treatment outcomes, it is recommended to strictly follow the product instructions for storage and use it under a doctor's guidance. Additionally, insulin should be kept in its original packaging, protected from moisture and light, and inspected regularly for changes in appearance.

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