What is the normal value for jaundice in infants?

Jul 10, 2025 Source: Cainiu Health
Dr. Zhou Xiaofeng
Introduction
In general, the normal values for neonatal jaundice should be determined according to the infant's age in days and birth circumstances. For full-term infants, serum bilirubin levels typically do not exceed 221 μmol/L, while for preterm infants, they usually do not exceed 257 μmol/L. Full-term infants commonly develop jaundice on the 2nd to 3rd day after birth, with bilirubin levels peaking on the 4th to 5th day. During this period, serum bilirubin levels within 221 μmol/L are considered normal.

Generally, the normal values for neonatal jaundice are determined based on gestational age and birth conditions. In full-term infants, serum bilirubin levels typically do not exceed 221 μmol/L, while in premature infants, they do not exceed 257 μmol/L. If abnormalities are detected, timely medical consultation is recommended. Detailed analysis is as follows:

Jaundice in full-term infants usually appears on days 2-3 after birth, peaks on days 4-5, and serum bilirubin levels within 221 μmol/L during this period are considered normal. The daily increase should not exceed 5 mg/dL, and jaundice typically subsides gradually within 7-10 days. During this time, the infant should remain alert, feed well, and show no other abnormal symptoms.

Due to weaker liver function, premature infants develop jaundice slightly later, and the resolution period may extend to 2-4 weeks. The peak serum bilirubin level may be slightly higher, and levels below 257 μmol/L are generally considered physiological. However, if bilirubin levels exceed this threshold or jaundice persists, it may indicate pathological jaundice.

When monitoring jaundice in infants, attention should be paid to the extent of skin yellowing and the rate of resolution. If bilirubin levels are abnormal or if symptoms such as refusal to feed or excessive sleepiness occur, prompt medical evaluation is necessary to avoid delayed intervention.

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