What is the normal level of neonatal jaundice?

Jul 11, 2025 Source: Cainiu Health

Dr. Shen Yonghua

Introduction

Under normal circumstances, the normal range for neonatal jaundice varies according to the number of days since birth and gestational age. For full-term infants, bilirubin levels should not exceed 6 mg/dL within 24 hours after birth, 9 mg/dL within 48 hours, and 15 mg/dL after 72 hours. For preterm infants, bilirubin levels should not exceed 18 mg/dL after 72 hours. Parents should seek medical attention promptly if they notice symptoms of jaundice in their newborn.

Generally, the normal range of neonatal jaundice varies according to the infant's age in days and gestational age. For full-term infants, the bilirubin level should not exceed 6 mg/dL within 24 hours after birth, 9 mg/dL within 48 hours, and 15 mg/dL after 72 hours. For preterm infants, the bilirubin level should not exceed 18 mg/dL after 72 hours. A detailed explanation is as follows:

Jaundice appearing 2-3 days after birth, with bilirubin levels within the normal range and accompanied by normal feeding and good mental status, is typically physiological jaundice. This condition results from the immature liver function of the newborn, causing temporarily slower bilirubin metabolism. It usually resolves naturally within 7-14 days and does not affect the infant's health.

If jaundice appears within 24 hours after birth, if bilirubin levels exceed the normal range for the corresponding age in days, or if jaundice reappears after fading, it may be pathological jaundice. Possible causes include hemolysis, infection, or biliary tract abnormalities. Prompt medical treatment is necessary, as excessively high bilirubin levels may damage the nervous system.

When parents notice symptoms of jaundice in their newborn, they should seek medical attention promptly and consult a healthcare professional. Additionally, parents should closely monitor the newborn's mental status, feeding, sleep, and urination/defecation to detect and manage any abnormalities in a timely manner.

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