What causes shingles?
Jul 17, 2025
Source: Cainiu Health
Dr. Liu Wenmin
Introduction
In general, herpes zoster may be caused by the reactivation of latent varicella-zoster virus, decreased immunity, excessive fatigue, trauma, systemic lupus erythematosus, or other factors. It is recommended to seek timely medical attention, identify the underlying cause, and undergo symptomatic treatment under a doctor's guidance. In daily life, one should maintain clean skin, wear loose and soft clothing, and minimize skin friction.
Generally, shingles may be caused by factors such as reactivation of latent varicella-zoster virus, decreased immunity, excessive fatigue, trauma, or systemic lupus erythematosus. It is recommended to seek timely medical consultation, identify the underlying cause, and undergo symptomatic treatment under a physician's guidance. Detailed explanations are as follows:
1. Reactivation of latent varicella-zoster virus: After the initial infection with varicella-zoster virus, the virus remains dormant in the sensory ganglia. When the body's condition changes, the virus may become activated and cause shingles. After disease onset, adequate rest is important, scratching the affected area should be avoided, and skin lesions should be protected from rupture and secondary infection.
2. Decreased immunity: Prolonged sleep deprivation and malnutrition can weaken immunity, preventing effective suppression of the latent virus and allowing viral replication that leads to disease. In daily life, sufficient sleep, a balanced diet, and moderate exercise should be maintained to enhance the body's resistance.
3. Excessive fatigue: Prolonged physical exhaustion can impair immune system function and increase the risk of developing shingles. It is important to maintain a reasonable balance between work and rest, avoid excessive physical strain, and ensure adequate rest.
4. Trauma: Mechanical injuries or burns may damage local nerve tissues, triggering activation of latent virus and inducing shingles. Wounds should be promptly treated after trauma, kept clean, and antiviral medications such as acyclovir cream, penciclovir cream, or recombinant human interferon α2b gel should be used as directed by a physician to prevent viral infection.
5. Systemic lupus erythematosus: This is an autoimmune disease that causes immune system dysfunction, impairing the body's ability to control viral infections and increasing susceptibility to shingles. Patients may follow medical advice to use immunomodulatory medications such as methylprednisolone tablets, hydroxychloroquine sulfate tablets, or mycophenolate mofetil dispersible tablets to regulate immunity and alleviate symptoms.
In daily life, maintaining clean skin and wearing loose, soft clothing to minimize skin friction is recommended. Additionally, maintaining a positive mindset and avoiding mental stress can aid in recovery.
