What are the seven best medications for treating rheumatism?

Jul 23, 2025 Source: Cainiu Health
Dr. Yang Tiesheng
Introduction
In general, there is no specific claim regarding the seven best medications for treating rheumatism. Some of the more effective drugs for treating rheumatism include Celecoxib capsules, Diclofenac Sodium sustained-release tablets, Prednisone Acetate tablets, Methotrexate tablets, and Leflunomide tablets. It is recommended to use these medications under a doctor's guidance. Additionally, maintaining healthy lifestyle habits while on medication is important.

Generally speaking, there is no such thing as the seven best medications for treating rheumatism. Some effective drugs for treating rheumatism include Celecoxib Capsules, Diclofenac Sodium Sustained-Release Tablets, Prednisone Acetate Tablets, Methotrexate Tablets, and Leflunomide Tablets. It is recommended to use these medications under the guidance of a doctor. A detailed explanation is as follows:

1. Celecoxib Capsules

Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) and a highly selective cyclooxygenase (COX-2) inhibitor. It achieves anti-inflammatory and analgesic effects by inhibiting prostaglandin production, helping alleviate pain caused by rheumatism. It has relatively better gastrointestinal safety, but long-term use may increase cardiovascular risks.

2. Diclofenac Sodium Sustained-Release Tablets

Diclofenac Sodium Sustained-Release Tablets are also nonsteroidal anti-inflammatory drugs. They have antipyretic, analgesic, and anti-rheumatic effects, and can inhibit cyclooxygenase activity, blocking the conversion of arachidonic acid into prostaglandins, thereby inhibiting the synthesis of leukotrienes and prostacyclin, exerting pain-relieving effects. They are suitable for treating pain caused by rheumatoid arthritis.

3. Prednisone Acetate Tablets

Prednisone Acetate Tablets belong to adrenocortical hormone medications and have anti-inflammatory, anti-allergic, and immunosuppressive effects. By suppressing inflammatory and immune responses, they can relieve symptoms and signs in patients with rheumatic diseases. These tablets are suitable for treating various rheumatic diseases but may cause adverse reactions such as osteoporosis and infections.

4. Methotrexate Tablets

Methotrexate Tablets are a foundational medication for treating rheumatoid arthritis and belong to synthetic disease-modifying antirheumatic drugs (DMARDs). They inhibit DNA synthesis by reducing adenosine synthetase activity and decrease the production of soluble interleukin-2 receptors, suppressing cell proliferation and inflammatory responses. Methotrexate has anti-inflammatory and immunosuppressive effects and can improve and delay the progression of rheumatic diseases.

5. Leflunomide Tablets

Leflunomide Tablets are immunosuppressants that directly inhibit the de novo biosynthesis of pyrimidines, thereby suppressing the proliferation of lymphocytes and B cells, exerting anti-rheumatic effects. Leflunomide Tablets are primarily used for treating rheumatoid arthritis in adults and can relieve symptoms such as joint pain and swelling.

During medication, it is important to develop good lifestyle habits and avoid consuming spicy and irritating foods, such as pepper, chili peppers, and garlic, as they may hinder recovery.

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