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What is the best medication for lowering blood lipids?

Jul 31, 2025 Source: Cainiu Health
Dr. Tian Hongbo
Introduction
In general, there is no single "best" lipid-lowering medication. Lipid-lowering drugs include atorvastatin calcium tablets, rosuvastatin calcium capsules, simvastatin tablets, fenofibrate capsules, bezafibrate tablets, and others. It is recommended to follow medical advice when taking these medications. Additionally, maintaining a regular作息 (作息 should be translated as作息规律 here, but since it's repeated in the original text, it might be a typo or redundancy) lifestyle, avoiding late nights, and reducing mental stress are also important in daily life to help prevent elevated blood lipid levels. (Note: The term "作息规律" was repeated in the original Chinese text. For natural English phrasing, it has been translated once as "maintaining a regular lifestyle".)

Generally speaking, there is no such thing as the best lipid-lowering medication. Lipid-lowering drugs include atorvastatin calcium tablets, rosuvastatin calcium capsules, simvastatin tablets, fenofibrate capsules, bezafibrate tablets, etc. It is recommended to follow medical advice when using these medications. Detailed explanations are as follows:

　　

1. Atorvastatin Calcium Tablets

Atorvastatin calcium tablets inhibit cholesterol synthesis and strongly reduce low-density lipoprotein cholesterol (LDL-C). They can also mildly increase high-density lipoprotein cholesterol (HDL-C) levels and lower triglycerides. These tablets can be used for the prevention of cardiovascular diseases. Adverse reactions include abnormal liver function and muscle pain.

2. Rosuvastatin Calcium Capsules

Rosuvastatin calcium capsules significantly lower low-density lipoprotein cholesterol levels and have anti-inflammatory effects and the ability to stabilize atherosclerotic plaques. They can be used for primary and secondary prevention of cardiovascular disease. During use, changes in liver enzymes, creatine kinase levels, and effects on glucose metabolism should be monitored.

3. Simvastatin Tablets

Simvastatin tablets effectively lower blood lipids and reduce the risk of cardiovascular events. However, drug interactions may occur when used with certain other medications—for example, combining with amiodarone may increase the risk of myopathy.

4. Fenofibrate Capsules

Fenofibrate capsules primarily lower triglyceride levels and can also increase high-density lipoprotein cholesterol. They are suitable for treating hypertriglyceridemia. Possible adverse reactions include gastrointestinal discomfort and abnormal liver function.

5. Bezafibrate Tablets

Bezafibrate tablets regulate blood lipids and improve lipoprotein metabolism. They can be used for mixed hyperlipidemia but may cause side effects such as muscle symptoms and gallstones.

In daily life, it is also important to maintain a healthy lifestyle, avoid staying up late, and reduce mental stress to help prevent elevated lipid levels.

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