Is the hepatitis B virus carrier negative or what?

Aug 01, 2025 Source: Cainiu Health

Dr. Gao Jun

Introduction

Under normal circumstances, a hepatitis B virus carrier refers to an individual who carries the hepatitis B virus. The hepatitis B surface antigen of such carriers is positive, rather than negative. Hepatitis B carriers typically do not exhibit obvious clinical symptoms, but there may be ongoing viral replication and inflammatory activity within the liver. Therefore, it is important to take appropriate measures to prevent transmission to family members and the surrounding population.

Generally speaking, a hepatitis B virus carrier refers to a carrier of the hepatitis B virus. The hepatitis B surface antigen of a hepatitis B virus carrier is positive rather than negative. A detailed analysis is as follows:

The "five-panel hepatitis B test" includes hepatitis B surface antigen, hepatitis B surface antibody, hepatitis B e antigen, hepatitis B e antibody, and hepatitis B core antibody. The hepatitis B surface antigen is the outer shell protein of the hepatitis B virus, and a positive result indicates the presence of hepatitis B virus in the body. There are generally two common situations among hepatitis B virus carriers. One is positive for hepatitis B surface antigen, hepatitis B e antigen, and hepatitis B core antibody, known as "big three positive" ("big three阳"). This indicates active replication of the hepatitis B virus in the body and strong infectivity. The other situation is positive for hepatitis B surface antigen, hepatitis B e antibody, and hepatitis B core antibody, known as "small three positive" ("small three阳"). In this case, viral replication is relatively low, although the virus is still somewhat infectious.

Hepatitis B virus carriers usually do not exhibit significant clinical symptoms, but there may be ongoing viral replication and inflammatory activity within the liver. Therefore, it is important to take appropriate measures to prevent transmission to family members and others nearby. Additionally, hepatitis B virus carriers should develop healthy lifestyle and dietary habits, follow a scientifically balanced diet, avoid alcohol consumption, refrain from excessive fatigue, maintain a positive mindset, and undergo regular follow-up examinations.

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