Why do uterine fibroids develop?
Aug 18, 2025
Source: Cainiu Health
Dr. Zhang Lu
Introduction
Uterine fibroids may be caused by abnormal hormone levels, age-related factors, endometritis, polycystic ovary syndrome (PCOS), adenomyosis, and other factors. It is recommended to seek timely medical attention, identify the underlying cause, and undergo symptomatic treatment under a doctor's guidance. In daily life, maintain emotional stability, avoid prolonged anxiety and stress, and follow a balanced diet by consuming more fiber-rich foods such as spinach and oats.
Generally, uterine fibroids may be caused by abnormal hormone levels, age-related factors, endometritis, polycystic ovary syndrome (PCOS), adenomyosis, and other factors. It is recommended to seek timely medical consultation, identify the underlying cause, and undergo symptomatic treatment under a doctor's guidance. Detailed analysis is as follows:
1. Abnormal hormone levels: Prolonged high levels of estrogen and progesterone in women can continuously stimulate the proliferation of uterine smooth muscle tissue, thereby inducing uterine fibroids. It is important to maintain regular sleep patterns, avoid staying up late, and reduce consumption of high-estrogen foods such as royal jelly and bee pollen.
2. Age-related factors: Women of childbearing age between 30–50 years typically have active ovarian function and robust hormone secretion. The uterine smooth muscle is more susceptible to hormonal influences, leading to abnormal proliferation and a higher risk of fibroids compared to other age groups. Regular gynecological ultrasound examinations are recommended to closely monitor changes in uterine morphology for early detection and intervention.
3. Endometritis: Often caused by bacterial infections such as streptococcus or Escherichia coli, repeated inflammation can damage the stability of the uterine internal environment by irritating the endometrium and muscle layer, increasing the likelihood of developing uterine fibroids. Maintaining genital hygiene is important, and during illness, anti-infective medications such as metronidazole tablets, clindamycin capsules, and levofloxacin hydrochloride tablets may be used as directed by a physician.
4. Polycystic ovary syndrome (PCOS): Endocrine disorders leading to elevated androgen levels and ovulation problems can cause imbalances between estrogen and progesterone in the body, continuously stimulating uterine smooth muscle and increasing the risk of fibroids. Weight control is essential, and medications such as metformin hydrochloride tablets, spironolactone tablets, and ethinyl estradiol cyproterone acetate tablets may be used under medical guidance to regulate the endocrine system and restore hormonal balance.
5. Adenomyosis: The invasion and growth of endometrial tissue into the uterine muscle layer can lead to uterine enlargement and hormonal metabolic disorders, creating conditions favorable for the development of uterine fibroids. This condition is often accompanied by dysmenorrhea and increased menstrual bleeding. Mild symptoms may be relieved with heat application, while more severe symptoms may require medications such as triptolide capsules, dydrogesterone tablets, or norethisterone tablets as directed by a physician to inhibit endometrial growth.
In daily life, maintaining emotional stability and avoiding prolonged anxiety or stress is important. A balanced diet rich in dietary fiber, such as spinach and oats, should be emphasized. Long-term use of estrogen-containing supplements should be avoided. Maintaining regular sleep patterns and moderate exercise can help promote uterine health.
