Can Mecobalamin and Epalrestat Tablets be taken long-term?

Aug 18, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Mecobalamin, as a neurotrophic drug, is commonly used in the treatment of peripheral neuropathy. If the medical condition requires and there are no significant adverse reactions after administration, it may be used long-term under a doctor's evaluation to assist in nerve repair and functional recovery. During this period, blood routine and other indicators should be monitored. Epalrestat tablets are used to improve diabetic neuropathy if the patient's blood glucose is stably controlled.

Mecobalamin is commonly available in tablet form. Generally, whether Mecobalamin and Epalrestat tablets can be taken long-term depends on the individual patient's condition. Most patients can take them long-term under a doctor's guidance, although regular monitoring is necessary. Detailed analysis is as follows:

As a neurotrophic drug, mecobalamin is commonly used in the treatment of peripheral neuropathy. If the medical condition requires long-term use and no significant adverse reactions occur after administration, it may be used long-term following a doctor's evaluation to aid nerve repair and functional recovery, with attention given to monitoring blood parameters such as complete blood count during this period.

Epalrestat tablets are used to improve diabetic neuropathy. If a patient's blood glucose is well-controlled and no allergic reactions or abnormal liver function occur after taking the medication, it can be taken long-term as directed by a physician, although regular liver function tests are necessary to avoid drug accumulation and its potential impact on the body.

During the course of taking these two medications, strict adherence to medical instructions is essential; patients should not decide the duration of treatment on their own. If discomfort or abnormal test indicators occur, the doctor should be informed promptly so they can determine whether to continue the medication or adjust the treatment plan.