What are the causes of Parkinson's syndrome in children?
Aug 19, 2025
Source: Cainiu Health
Dr. Zhou Xiaofeng
Introduction
In general, children may develop Parkinson's syndrome due to factors such as genetic influences, incomplete nervous system development, adverse drug reactions, postencephalitic sequelae, or hepatolenticular degeneration. If symptoms such as limb tremors, slow movements, or muscle stiffness occur, it is recommended to seek timely diagnosis and treatment at a reputable hospital. A detailed analysis is as follows:
Generally, children developing Parkinsonism may be caused by factors such as genetic influences, underdeveloped nervous systems, adverse drug reactions, postencephalitic sequelae, Wilson's disease (hepatic-lenticular degeneration), and other reasons. If symptoms such as limb tremors, slow movements, or muscle rigidity appear, it is recommended to seek timely diagnosis and treatment at a regular hospital. Detailed analysis is as follows:
1. Genetic Influences
Some children may have specific gene mutations due to family heredity, leading to abnormal dopamine regulation by the nervous system and causing Parkinsonism. In such cases, regular neurological examinations are necessary for early detection and intervention. Daily activities can include limb coordination training, such as rope jumping and ball bouncing.
2. Underdeveloped Nervous System
Children's nervous systems are not yet fully mature, and their regulation of neurotransmitters is relatively weak, which may lead to abnormal dopamine secretion and increase the risk of disease. As children grow older, the nervous system gradually matures, and symptoms may improve. During this time, it is important to ensure sufficient sleep and nutrition to promote nervous system development.
3. Adverse Drug Reactions
Long-term use of certain antipsychotic medications, such as haloperidol tablets, may affect dopamine receptor function, causing symptoms of Parkinsonism in children. If symptoms are mild, the dosage may be reduced or alternative medications used under a doctor's guidance, while closely monitoring symptom changes.
4. Postencephalitic Sequelae
After brain inflammation caused by viral or bacterial infections, dopamine-producing neurons in the substantia nigra region of the brain may be damaged, leading to reduced dopamine secretion and causing Parkinsonism. Under medical guidance, drugs such as vitamin B1 tablets, vitamin B12 injections, and sodium citicoline injections may be used to nourish the nerves, along with rehabilitation therapy.
5. Wilson's Disease (Hepatic-Lenticular Degeneration)
This is an autosomal recessive genetic disorder where abnormal copper metabolism leads to copper accumulation in the brain, damaging the basal ganglia and causing Parkinsonism-like symptoms. Under medical guidance, drugs such as penicillamine tablets, dimercaptosuccinic acid capsules, and zinc gluconate oral solution may be used to promote copper excretion. High-copper foods such as animal liver and nuts should also be avoided.
In daily life, ensure children maintain regular sleep patterns and avoid excessive fatigue; maintain a balanced diet; communicate frequently with children to keep their mood positive; if children have relevant medical histories, regular neurological checkups should be conducted to detect and address any issues promptly.
