What is the normal value for Helicobacter pylori?

Aug 27, 2025 Source: Cainiu Health
Dr. Shen Yonghua
Introduction
Under normal circumstances, there is no unified standard for the normal value of Helicobacter pylori, and the interpretation depends on the detection method used. Clinically common methods include carbon-13 and carbon-14 urea breath tests, as well as histological examination during gastroscopy, each having its own reference range. Results beyond the reference range suggest possible infection. The test results should be interpreted according to the specific reference range of the method used. If infection is indicated, further evaluation is needed.

Generally, there is no uniform standard for the normal value of Helicobacter pylori, and the interpretation depends on the detection method used. Clinically common methods such as carbon-13 and carbon-14 urea breath tests, as well as gastroscopic biopsy, each have their own reference ranges. Results exceeding these ranges suggest possible infection. Detailed analysis is as follows:

The carbon-13 urea breath test is a commonly used non-invasive detection method, with a reference range typically of 0-4 dpm. If the measured value falls within this range, it indicates no infection or very low infection level; if the value exceeds 4 dpm, it suggests possible Helicobacter pylori infection. The reference range for the carbon-14 urea breath test is generally 0-100 dpm. A value below 100 dpm is considered negative, while a value above 100 dpm is positive, indicating the need for further evaluation to determine whether treatment is required.

Tissue biopsy and histopathological examination under gastroscopy determine infection by detecting the presence of Helicobacter pylori in gastric mucosal tissue. If no bacteria are detected, the result is considered normal; if bacteria are found, regardless of the quantity, it indicates infection. Additionally, the reference value for serum antibody testing is negative; a positive result only indicates past infection and does not reflect current infection status. Comprehensive judgment should be made in combination with other test results.

After testing, results should be interpreted according to the specific reference range of the detection method used. If infection is indicated, a standardized treatment plan should be followed, along with attention to dietary hygiene to reduce disease risk.

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