How are uterine fibroids formed?

Sep 01, 2025 Source: Cainiu Health

Dr. Zhang Lu

Introduction

In general, the formation of uterine fibroids may be caused by factors such as genetic influences, hormonal imbalances, aging, endometritis, and adenomyosis. It is recommended to seek timely medical attention, identify the underlying cause, and undergo symptomatic treatment under a doctor's guidance. Daily life should involve maintaining emotional stability, avoiding prolonged anxiety and depression, and reducing the impact of psychological stress on hormone levels.

Generally, the formation of uterine fibroids may be caused by factors such as genetic influences, hormonal imbalances, aging, endometritis, and adenomyosis. It is recommended to seek timely medical consultation, identify the underlying cause, and undergo symptomatic treatment under a doctor's guidance. Detailed analysis is as follows:

1. Genetic Factors: Individuals with a family history of uterine fibroids may inherit susceptibility genes, which increase the sensitivity of uterine smooth muscle to hormones, making it prone to abnormal proliferation and fibroid formation. This often occurs in adolescent or young women. Those with a family history should start regular gynecological ultrasound examinations earlier—at least once or twice a year—to ensure early detection.

2. Hormonal Imbalance: Excessive secretion of estrogen and progesterone in women of reproductive age can stimulate abnormal proliferation of uterine smooth muscle, gradually leading to fibroid formation. This is commonly seen in women aged 20–40 years. Maintaining a regular lifestyle, avoiding staying up late, reducing intake of estrogen-containing supplements, and consuming more soy products, vegetables, and other foods rich in dietary fiber can help regulate hormone balance and reduce the risk of fibroid development.

3. Aging: As women age, ovarian function changes and hormonal regulation capacity declines, making uterine smooth muscle more prone to abnormal proliferation and increasing the likelihood of fibroid formation. This is commonly observed in perimenopausal women. Regular moderate exercise, such as brisk walking or yoga, can enhance metabolic capacity and help maintain hormonal stability.

4. Endometritis: Long-term bacterial infection and inflammation of the endometrium can stimulate uterine smooth muscle proliferation, potentially inducing fibroids, accompanied by menstrual irregularities and lower abdominal pain. Patients should follow medical advice to use medications such as cefuroxime axetil tablets, metronidazole tablets, and levofloxacin hydrochloride capsules to control inflammation. Reducing inflammation can help eliminate triggers for fibroid development.

5. Adenomyosis: The invasion of endometrial tissue into the uterine muscle layer can lead to disordered proliferation of muscle tissue, possibly accompanied by fibroid formation, manifesting as worsening dysmenorrhea and increased menstrual flow. For mild symptoms, medications such as gestrinone capsules, danazol capsules, and ibuprofen sustained-release capsules may be used under medical guidance to relieve symptoms. If fibroids are small, laparoscopic lesion resection can be performed to remove diseased tissue and reduce stimulation to the uterine smooth muscle.

In daily life, maintaining emotional stability, avoiding long-term anxiety and depression, and reducing psychological stress can help minimize the impact on hormone levels. Practicing good menstrual hygiene and avoiding strenuous exercise during menstruation through effective lifestyle management can lower the risk of developing and progressing uterine fibroids.

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What should I do if I become pregnant with uterine fibroids?

In general, women who become pregnant with uterine fibroids should manage their condition through enhanced prenatal monitoring, adjustment of daily activities, attention to nutritional diet, awareness of physical symptoms, and cooperation with medical interventions. It is important to maintain a positive mindset during pregnancy and avoid excessive anxiety, as anxious emotions may affect hormone levels and jeopardize pregnancy stability. At the same time, maintain close communication with the physician to stay informed about both maternal and fetal conditions.

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Is uterine fibroid serious?

In general, the severity of uterine fibroids needs to be determined based on their size, symptoms, and growth pattern. Small fibroids without symptoms are usually not serious and do not require special treatment; however, fibroids that cause significant symptoms or grow rapidly are considered more severe and require timely intervention. In daily life, it is important to maintain a regular作息 (作息 should be translated as "routine" or "lifestyle rhythm"), avoid excessive fatigue, limit the intake of foods high in estrogen, and reduce the risk of fibroid growth.

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How are uterine fibroids caused?

Under normal circumstances, the main causes of uterine fibroids include hormonal changes, aging, endometritis, polycystic ovary syndrome, and adenomyosis. If discomfort symptoms occur, it is recommended to seek timely medical treatment at a正规 hospital. In daily life, one should maintain external genital hygiene and avoid unclean sexual activity; maintain a regular diet and balanced nutrition.

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What causes bleeding during ovulation?

In general, bleeding during the ovulation period may be caused by a temporary decline in estrogen levels, vigorous exercise, endometritis, cervical polyps, submucosal uterine fibroids, or other factors. It is recommended to seek timely medical attention, identify the underlying cause, and receive symptomatic treatment under a doctor's guidance. Additionally, it is important to maintain menstrual hygiene, change sanitary products frequently, and avoid unclean sexual practices.