What is Ankylosing Spondylitis?

Sep 08, 2025 Source: Cainiu Health
Dr. Chen Jian
Introduction
In general, ankylosing spondylitis is a chronic inflammatory disease that primarily affects the spine, sacroiliac joints, and surrounding joints, leading to joint adhesion and stiffness. In severe cases, it may impair spinal mobility. In daily life, if symptoms such as persistent lower back pain and stiffness occur, prompt professional examination is necessary to confirm the diagnosis.

Generally speaking, ankylosing spondylitis is a chronic inflammatory disease that primarily affects the spine, sacroiliac joints, and surrounding joints. It can cause joint adhesion and stiffness, and in severe cases, may impair spinal mobility functions. Detailed analysis is as follows:

From the perspective of disease pathology, ankylosing spondylitis belongs to autoimmune diseases. Its causes are associated with genetic factors, immune system dysfunction, environmental factors, and it commonly occurs in young and middle-aged populations. The disease often starts at the sacroiliac joints initially, with inflammation gradually spreading upward to the spine. It may also affect peripheral joints such as the hip and knee joints, leading to damage to joint cartilage and bone tissue.

Regarding common symptoms, patients often experience lower back pain and stiffness in the early stages. Stiffness tends to be more pronounced upon waking in the morning but may temporarily improve after some activity. As the condition progresses, pain may intensify, the spine may gradually lose its normal physiological curvature, and spinal deformities may even develop, affecting daily activities.

In daily life, if persistent low back or spinal pain and stiffness or other suspected symptoms occur, timely professional examination is necessary for accurate diagnosis. After diagnosis, standardized treatment combined with regular rehabilitation exercises can effectively control inflammation, alleviate symptoms, slow disease progression, and maintain normal functional abilities.

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