Can ibuprofen cause drowsiness?

Sep 10, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Common dosage forms of ibuprofen include tablets and capsules. Generally, ibuprofen is a commonly used nonsteroidal anti-inflammatory drug (NSAID), primarily used to relieve pain and reduce fever. Whether it causes drowsiness depends on individual circumstances. If drowsiness occurs during ibuprofen use, driving, operating precision instruments, or performing high-altitude work should be avoided to prevent accidents.

Common formulations of ibuprofen include tablets and capsules. Generally, ibuprofen is a commonly used nonsteroidal anti-inflammatory drug (NSAID), primarily used to relieve pain and reduce fever. Whether it causes drowsiness depends on specific circumstances. Detailed analysis is as follows:

If a patient takes a single-ingredient ibuprofen formulation and has no special reaction to its components, drowsiness typically does not occur. These formulations primarily target pain and fever-related pathways and do not contain sedative ingredients. Most people can carry out normal daily activities after taking the medication without experiencing significant sleepiness.

If a patient takes a compound formulation containing ibuprofen or is particularly sensitive to ibuprofen, drowsiness may occur. Other ingredients in compound formulations may have sedative effects, which can easily cause sleepiness when combined. Some sensitive individuals may experience mild central nervous system depression after taking the medication, manifesting as fatigue or sleepiness.

If drowsiness occurs during ibuprofen use, patients should avoid driving, operating precision instruments, or performing high-altitude work to prevent accidents. Before taking the medication, carefully check the drug's ingredients to determine whether it is a compound formulation. If drowsiness persists or is accompanied by other symptoms such as dizziness or nausea, discontinue the medication promptly and consult a doctor to adjust the treatment plan.

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