Can ibuprofen be taken with amoxicillin?

Common dosage forms of ibuprofen and amoxicillin include tablets and capsules. Generally, ibuprofen can be taken together with amoxicillin. Detailed explanation is as follows:

Ibuprofen belongs to non-steroidal anti-inflammatory drugs (NSAIDs) and mainly alleviates pain and reduces fever by inhibiting prostaglandin synthesis, but it does not have antibacterial effects. Amoxicillin is a penicillin-class antibiotic effective only against bacterial infections; it kills bacteria by inhibiting bacterial cell wall synthesis but cannot relieve pain or fever. When fever and pain are caused by bacterial infection, these two medications act on different targets and do not interfere with each other's efficacy. Taking them together can eliminate bacteria while simultaneously relieving discomfort symptoms.

Before taking these medications, confirm the presence of a bacterial infection. Do not blindly combine amoxicillin just because of fever or pain to avoid developing drug resistance. Each medication should be taken according to its recommended dosage and frequency; do not arbitrarily increase or decrease the dose. Monitor your body's response during treatment. If rashes, diarrhea, nausea, or other discomforts occur, or if symptoms do not improve, discontinue the medication promptly and seek medical advice. Patients with a history of penicillin allergy, gastrointestinal diseases, or impaired liver or kidney function must consult a healthcare professional before using these medications.