Which value in a complete blood count (CBC) should be checked for anemia?

Sep 16, 2025 Source: Cainiu Health
Dr. Liu Feng
Introduction
In general, when patients with anemia undergo a routine blood test, key indicators such as red blood cell count, hemoglobin concentration, hematocrit, mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) are primarily evaluated. These parameters reflect the presence and type of anemia from different perspectives. After testing, the results can be comprehensively analyzed to assess the anemia condition, and daily management may include dietary adjustments.

Generally, when a complete blood count is performed on patients with anemia, the main indicators to focus on include red blood cell count, hemoglobin concentration, hematocrit, mean corpuscular volume, and mean corpuscular hemoglobin. These indicators can reflect the presence and type of anemia from different perspectives. The specific analysis is as follows:

1. Red Blood Cell Count: This indicator reflects the number of red blood cells per unit volume of blood. A value below the normal range suggests possible anemia. A reduced red blood cell count leads to decreased oxygen-carrying capacity of the blood.

2. Hemoglobin Concentration: This is the most direct indicator for diagnosing anemia. When the value falls below the normal standard, anemia can be confirmed. The lower the value, the more severe the anemia typically is, directly affecting oxygen supply to various organs in the body.

3. Hematocrit: This refers to the percentage of red blood cell volume in the total blood volume. A decreased hematocrit often occurs simultaneously with reductions in red blood cell count and hemoglobin concentration. It assists in assessing the severity of anemia; the lower the value, the smaller the proportion of red blood cells in the blood.

4. Mean Corpuscular Volume: This measures the average size of individual red blood cells. A lower-than-normal value may suggest iron deficiency anemia, while a higher-than-normal value may be associated with megaloblastic anemia. It helps in the preliminary determination of the type of anemia.

5. Mean Corpuscular Hemoglobin: This reflects the average amount of hemoglobin contained within individual red blood cells. Abnormalities in this indicator are also related to the type of anemia—for example, a decreased value is commonly seen in iron deficiency anemia, while an increased value may indicate megaloblastic anemia.

After testing, a comprehensive assessment of anemia can be made by combining all the indicators. In daily life, dietary adjustments to increase intake of foods rich in iron and folic acid—such as lean meat, animal liver, and leafy green vegetables—along with maintaining a regular sleep schedule, can help improve conditions related to anemia.

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