What are the reasons for being unable to get pregnant?

Sep 16, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, the main causes of difficulty in conceiving include excessive mental stress, improper timing of conception attempts, blocked fallopian tubes, polycystic ovary syndrome (PCOS), and endometrial polyps. If this situation occurs, it is recommended to seek timely medical evaluation and treatment at a reputable hospital. In daily life, maintain a positive mindset and avoid excessive anxiety; eat a balanced diet and supplement with folic acid and vitamins.

Generally, the main reasons for not being able to conceive include excessive mental stress, improper timing of conception attempts, fallopian tube blockage, polycystic ovary syndrome (PCOS), and endometrial polyps. If this situation occurs, it is recommended to seek timely diagnosis and treatment at a reputable hospital. Detailed analysis is as follows:

1. Excessive Mental Stress

Long-term anxiety and tension can affect the hypothalamic-pituitary-ovarian axis function, leading to ovulation disorders and decreased fertility. Stress can be relieved through exercise, meditation, maintaining regular sleep patterns, communicating more with your partner, and avoiding excessive focus on pregnancy outcomes.

2. Improper Timing of Conception Attempts

Failing to accurately identify the ovulation period can prevent sperm and egg from meeting, resulting in conception failure. Ovulation test strips combined with basal body temperature measurements can help monitor ovulation, and appropriately scheduling intercourse around the ovulation period can increase the chances of conception.

3. Fallopian Tube Blockage

Infections can cause inflammation, leading to adhesion and blockage of the fallopian tube mucosa, hindering the union of sperm and egg. Under a doctor's guidance, medications such as levofloxacin hydrochloride capsules, cefuroxime axetil tablets, and azithromycin dispersible tablets can be taken to control inflammation. In severe cases, tubal irrigation or laparoscopic tubal anastomosis may be required.

4. Polycystic Ovary Syndrome (PCOS)

Hormonal imbalances can lead to ovulatory dysfunction and abnormal follicle development, affecting fertility. Under a doctor's guidance, medications such as dydrogesterone tablets, medroxyprogesterone acetate tablets, and letrozole tablets can be used to regulate hormones and promote ovulation. Weight management and reducing high-sugar, high-fat diets are also important.

5. Endometrial Polyps

Localized endometrial hyperplasia forms polyps, which can interfere with embryo implantation, making conception difficult. Under a doctor's guidance, medications such as progesterone capsules, drospirenone ethinylestradiol tablets, and desogestrel ethinylestradiol tablets may be used. If the polyps are large, hysteroscopic removal of endometrial polyps may be necessary.

In daily life, maintaining a positive mindset and avoiding excessive anxiety are important. A balanced diet supplemented with folic acid and vitamins, regular exercise to maintain a healthy weight, good personal hygiene to prevent reproductive system infections, and regular preconception checkups to detect and address issues early are also essential.