What is the difference between ibuprofen sustained-release capsules and ibuprofen tablets?

The main differences between ibuprofen sustained-release capsules and ibuprofen tablets are reflected in dosage form design, onset time, duration of action, dosing frequency, and applicable scenarios. The specific analysis is as follows:

1. Dosage Form Design: Ibuprofen sustained-release capsules use special sustained-release formulation technology, in which the drug is encapsulated within a sustained-release matrix; ibuprofen tablets are conventional tablets without special formulation structures. This difference in design directly determines the two formulations' drug release patterns and pharmacological characteristics.

2. Onset Time: After administration, ibuprofen tablets rapidly dissolve and release the drug, resulting in a relatively quick onset—effects are typically felt within 30 minutes to 1 hour. In contrast, ibuprofen sustained-release capsules gradually release the drug, leading to a slower onset, usually taking 1 to 2 hours before effects begin to appear.

3. Duration of Action: The drug release from ibuprofen sustained-release capsules is steady and prolonged, providing effects that last up to 12 hours. Ibuprofen tablets release the drug quickly but have a shorter duration of action, typically lasting only 4 to 6 hours, with a relatively rapid decline in efficacy.

4. Dosing Frequency: Due to differences in duration of action, ibuprofen sustained-release capsules need to be taken only twice daily to maintain therapeutic effect. Ibuprofen tablets, however, require more frequent dosing—typically 3 to 4 times per day—to ensure continuous pain relief and antipyretic effects.

5. Applicable Scenarios: Ibuprofen sustained-release capsules are suitable for situations requiring long-term or sustained pain relief, such as chronic arthritic pain. Ibuprofen tablets are better suited for acute pain or fever symptoms, such as sudden headaches or fever due to colds fever, where rapid symptom relief is needed.

Before using either medication, select the appropriate formulation based on your symptoms, and strictly follow the dosage and frequency instructions provided in the product label or by a healthcare provider. Neither medication should be used excessively or over prolonged periods. If symptoms persist for more than 3 consecutive days of treatment, seek medical attention promptly.