What medications have the same therapeutic effects as aspirin?

Nov 25, 2025 Source: Cainiu Health
Dr. Wang Lei
Introduction
Drugs with effects similar to aspirin include ibuprofen sustained-release capsules, acetaminophen tablets, sodium diclofenac enteric-coated tablets, naproxen dispersible tablets, and clopidogrel tablets. These medications all possess antipyretic, analgesic, or antiplatelet properties and should be appropriately selected based on specific indications. If there is a history of drug allergy, gastrointestinal disorders, or bleeding tendency, prompt medical evaluation is recommended.

Medications with similar effects to aspirin include ibuprofen sustained-release capsules, acetaminophen tablets, diclofenac sodium enteric-coated tablets, naproxen dispersible tablets, and clopidogrel hydrogen sulfate tablets. All of these drugs possess antipyretic, analgesic, or antiplatelet properties and should be rationally selected under medical guidance based on specific indications. Individuals with a history of drug allergy, gastrointestinal disorders, or bleeding tendencies should seek timely medical evaluation.

1. Ibuprofen Sustained-Release Capsules: Possess antipyretic, analgesic, and anti-inflammatory properties, effectively relieving mild to moderate pain and fever. Its anti-inflammatory effect in conditions such as rheumatoid arthritis is comparable to aspirin, while offering a milder and longer-lasting analgesic action.

2. Acetaminophen Tablets: Primarily used for antipyresis and pain relief. The antipyretic effect is comparable to aspirin, and it is effective against headaches, joint pain, and other types of pain. However, its anti-inflammatory effect is relatively weak, and it causes less gastrointestinal irritation than aspirin.

3. Diclofenac Sodium Enteric-Coated Tablets: Exhibit stronger antipyretic, analgesic, and anti-inflammatory effects than aspirin, effectively alleviating various types of pain and inflammatory responses. They also have certain antiplatelet activity, making them suitable for patients suffering from inflammation-related pain.

4. Naproxen Dispersible Tablets: Provide antipyretic, analgesic, and anti-inflammatory effects. Their anti-inflammatory action is long-lasting and can be used in chronic inflammatory conditions such as rheumatoid arthritis. The analgesic range is consistent with aspirin, with a relatively rapid onset of action.

5. Clopidogrel Hydrogen Sulfate Tablets: Like aspirin, this is an antiplatelet agent that prevents thrombosis by inhibiting platelet aggregation. It is commonly used for the prevention of cardiovascular and cerebrovascular diseases. It lacks significant antipyretic or anti-inflammatory effects and primarily focuses on antithrombotic efficacy.

When taking these medications, avoid concurrent use of multiple agents to reduce the risk of gastrointestinal damage. Taking them after meals can minimize gastric irritation, and alcohol consumption should be avoided. Select medications according to their approved indications and do not blindly substitute for aspirin to ensure safe medication use.

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