Can taking antiviral medication lead to cirrhosis?

Sep 18, 2025 Source: Cainiu Health
Dr. Gao Jun
Introduction
In general, whether taking antiviral medication will lead to liver cirrhosis depends on the medication regimen and control of the underlying disease. When antiviral drugs are taken properly and the primary condition is effectively controlled, cirrhosis usually does not develop. However, if the medication is used improperly or the underlying disease remains uncontrolled, progression to liver cirrhosis may occur. During antiviral treatment, patients must strictly follow their doctor's instructions.

In general, whether taking antiviral medication will lead to cirrhosis depends on the medication use and control of the underlying disease. When antiviral drugs are taken properly and the primary disease is effectively controlled, cirrhosis typically does not develop; however, improper use of medication or uncontrolled primary disease may lead to cirrhosis. The detailed analysis is as follows:

If a patient takes antiviral medication for viral liver diseases such as hepatitis B or hepatitis C, and strictly follows medical advice with proper medication use, the drugs can effectively suppress viral replication, reduce liver inflammation and damage, and prevent progression of liver fibrosis. In such cases, cirrhosis usually does not occur, and the risk of developing cirrhosis is actually reduced.

If a patient stops, reduces, or changes medications without authorization during antiviral treatment, resulting in poor viral control, the liver continues to suffer viral damage and recurrent inflammation, which may gradually progress to liver fibrosis and potentially evolve into cirrhosis. Additionally, if the patient engages in liver-damaging behaviors such as long-term alcohol consumption or chronic sleep deprivation, the likelihood of developing cirrhosis increases.

During antiviral treatment, patients must strictly follow medical instructions, avoid adjusting dosages or stopping medication on their own, and undergo regular follow-up tests including liver function and viral load. In daily life, they should maintain a regular routine, avoid alcohol, eat a light and easily digestible diet, and reduce the burden on the liver.