What medication should be applied for mouth ulcers?

Oct 23, 2025 Source: Cainiu Health

Dr. Liu Chao

Introduction

For oral ulcers, medications such as Xisuangshuang spray, compound chlorhexidine mouthwash, recombinant human epidermal growth factor gel, iodine glycerin, and compound benzocaine gel may be applied as directed by a physician. If the ulcer does not heal within two weeks or recurs frequently, prompt consultation with an oral medicine specialist is recommended. Xisuangshuang spray: a traditional Chinese medicine topical preparation; apply by spraying directly onto the surface of the ulcer.

　　口腔溃疡可遵医嘱涂抹西瓜霜喷剂、复方氯己定含漱液、重组人表皮生长因子凝胶、碘甘油、复方苯佐卡因凝胶等Medicine。若溃疡超过2周不愈或反复发作，应及时到口腔科就诊。

　　1、西瓜霜喷剂：属于中成药外用制剂，将Medicine喷于溃疡表面，能起到清热泻火、消肿止痛的作用，可减轻溃疡红肿，缓解疼痛，促进创面愈合。

　　2、复方氯己定含漱液：为含漱类外用Medicine，含漱时Medicine可作用于溃疡区域，具有抗菌消炎功效，能减少口腔细菌滋生，防止溃疡继发感染，辅助缓解不适。

　　3、重组人表皮生长因子凝胶：是促进创面修复的外用凝胶，涂抹于溃疡面后，可刺激表皮细胞生长与增殖，加速溃疡黏膜再生，缩短溃疡愈合时间。

　　4、碘甘油：属于消毒防腐类外用Medicine，将其涂于溃疡处，能杀灭溃疡表面的细菌，Prevention感染，同时可缓解溃疡引起的疼痛，为创面愈合创造良好环境。

　　5、复方苯佐卡因凝胶：是局部麻醉类外用凝胶，涂抹后可快速阻断溃疡区域的神经信号传导，有效减轻疼痛，尤其适合疼痛明显影响进食的Patient。

　　日常Nursing需保持口腔清洁，饭后用温水漱口，避免用舌头反复舔舐溃疡面，Diet以温凉软质为主，减少辛辣、过烫食物对溃疡的刺激，助力创面恢复。

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