What medication should be taken for oral inflammation?

Oct 27, 2025 Source: Cainiu Health

Dr. Liu Chao

Introduction

In general, oral inflammation is an inflammatory condition caused by infection or irritation of the oral mucosa, gums, or throat. Common symptoms include redness and swelling of the mouth, pain, ulcers, and discomfort during swallowing. Patients may follow medical advice to use medications such as metronidazole mouthwash, amoxicillin capsules, compound chlorhexidine mouthwash, cefuroxime axetil tablets, and vitamin C tablets for treatment.

Generally, oral inflammation is an inflammatory condition caused by infection or irritation of the oral mucosa, gums, or throat. Common symptoms include redness and swelling of the mouth, pain, ulcers, and discomfort during swallowing. Patients may follow medical advice to use medications such as metronidazole mouthwash, amoxicillin capsules, compound chlorhexidine mouthwash, cefuroxime axetil tablets, and vitamin C tablets for treatment. Specific details are as follows:

1. Metronidazole Mouthwash

The main ingredient is metronidazole, which has a strong bactericidal effect against anaerobic bacteria in the oral cavity. It inhibits the growth of harmful bacteria in gingival pockets and on ulcer surfaces, reduces local inflammatory responses, and relieves redness, swelling, and pain. It is suitable for gingivitis, periodontitis, and ulcerative oral inflammation caused by anaerobic bacterial infections.

2. Amoxicillin Capsules

This medication belongs to the penicillin class of antibiotics. It exerts its bactericidal effect by inhibiting bacterial cell wall synthesis, eliminating Gram-positive bacteria and some Gram-negative bacteria in the oral cavity, controlling the spread of infection, and promoting resolution of inflammation. It is indicated for acute gingivitis and oral mucositis caused by bacterial infections.

3. Compound Chlorhexidine Mouthwash

Containing chlorhexidine and metronidazole, this mouthwash provides broad-spectrum antibacterial action along with anti-anaerobic effects. It helps clean the oral cavity, reduce bacterial proliferation, alleviate mucosal redness and swelling, and prevent secondary infections. It is used as adjunctive therapy for various types of bacterial oral inflammations, including gingivitis and angular cheilitis.

4. Cefuroxime Axetil Tablets

A second-generation cephalosporin antibiotic, it exhibits antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria. By inhibiting bacterial cell wall synthesis, it kills pathogenic bacteria, effectively controls moderate to severe oral bacterial infections, and alleviates inflammatory symptoms. It is suitable for severe gingivitis and pericoronitis caused by bacterial infections.

5. Vitamin C Tablets

Vitamin C participates in collagen synthesis, enhances the resilience of oral mucosa, promotes mucosal repair, improves mucosal resistance, helps reduce inflammatory damage, and lowers the risk of recurrent inflammation. It is indicated for cases of fragile oral mucosa and recurrent inflammation due to vitamin C deficiency, or as an adjunctive treatment in oral inflammatory conditions.

To maintain oral health, it is important to practice good oral hygiene—brush teeth twice daily with a soft-bristled toothbrush and rinse after meals. Avoid consuming excessively hot, spicy, or hard foods such as hot pot, chili peppers, and nuts. Drink plenty of water to stay hydrated and consume more fresh fruits and vegetables. Maintain a regular sleep schedule, avoid staying up late, strengthen overall immunity, and reduce the likelihood of developing oral inflammation.

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