What anti-inflammatory medication should be taken for appendicitis?

Generally, appendicitis is often caused by bacterial infection following obstruction of the appendix lumen. Common symptoms include shifting pain to the right lower abdomen, fever, nausea, and others. Patients may take medications such as cefuroxime axetil tablets, metronidazole tablets, levofloxacin tablets, amoxicillin capsules, and cefixime dispersible tablets under medical guidance. Specific details are as follows:

1. Cefuroxime Axetil Tablets

This medication belongs to the second-generation cephalosporin antibiotics. It exerts bactericidal effects by inhibiting bacterial cell wall synthesis. It has antimicrobial activity against both Gram-positive and Gram-negative bacteria commonly involved in appendicitis, such as *Escherichia coli* and streptococci. It is suitable for mild cases of simple appendicitis and can help control the progression of inflammation.

2. Metronidazole Tablets

A nitroimidazole-class antibacterial agent, metronidazole interferes with bacterial DNA synthesis, leading to bacterial death. It has potent bactericidal activity against anaerobic bacteria, which are frequently present in appendicitis infections. Therefore, this drug is often used in combination with other antibiotics to enhance anti-infective efficacy, especially in cases of appendicitis associated with anaerobic infection.

3. Levofloxacin Tablets

As a broad-spectrum quinolone antibiotic, levofloxacin inhibits bacterial DNA gyrase activity, thereby preventing bacterial DNA replication. It is effective against common pathogens causing appendicitis, such as *Escherichia coli* and *Klebsiella pneumoniae*. It is suitable for patients who are allergic to cephalosporins or those with moderately severe appendicitis.

4. Amoxicillin Capsules

This drug belongs to the penicillin class of antibiotics. It kills bacteria by disrupting their cell walls and has antimicrobial effects against susceptible organisms such as streptococci, staphylococci, and *Escherichia coli*. It is appropriate for mild cases of simple appendicitis or as an adjunctive postoperative anti-infective treatment.

5. Cefixime Dispersible Tablets

A third-generation cephalosporin antibiotic, cefixime has a broad antimicrobial spectrum and enhanced activity against Gram-negative bacteria. By inhibiting bacterial cell wall synthesis, it is particularly effective against pathogens like *Escherichia coli* and *Proteus mirabilis* that commonly cause appendicitis. It is indicated for patients with moderate symptoms and can effectively prevent the spread of inflammation.

In daily life, it is important to avoid overeating, reduce intake of spicy and greasy foods (such as fried chicken and chili peppers), and refrain from strenuous exercise after meals to lower the risk of appendix lumen obstruction. If symptoms such as worsening abdominal pain or fever occur, prompt medical attention is necessary to prevent delayed treatment.