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Can Roxithromycin treat allergic rhinitis?

Nov 06, 2025 Source: Cainiu Health
Dr. Lu Cheng
Introduction
In general, roxithromycin is not used to treat allergic rhinitis, but it may be used as an adjunct in specific cases with concurrent infection. Before using roxithromycin, it is essential to confirm the presence of bacterial infection, and self-medication should be avoided. The medication should be taken at the full prescribed dose and for the complete duration as directed by a physician. Do not discontinue or alter the dosage arbitrarily during treatment to prevent the development of bacterial resistance.

Generally, roxithromycin is not used to treat allergic rhinitis, but it may be used as an adjunct in specific cases involving secondary bacterial infections. The detailed explanation is as follows:

Allergic rhinitis is a non-infectious inflammatory response of the nasal mucosa triggered by the immune system upon exposure to allergens. Its core pathological mechanism is unrelated to bacterial infection. Roxithromycin is an antibiotic that primarily works by inhibiting bacterial growth and reproduction, making it effective only against bacterial infections. It cannot block the immune-mediated inflammatory reactions caused by allergens, nor can it relieve allergic symptoms such as nasal itching, sneezing, or runny nose. Therefore, roxithromycin is not suitable for treating allergic rhinitis. However, if patients with allergic rhinitis develop secondary bacterial infections due to prolonged nasal mucosal congestion and swelling, roxithromycin may be used under medical supervision to help control the bacterial infection and reduce infection-related inflammation.

Before using roxithromycin, it is essential to confirm the presence of a bacterial infection; self-medication should be avoided. The medication must be taken at the prescribed dose and for the full duration as directed by a physician. Do not stop taking the drug or adjust the dosage arbitrarily to prevent the development of bacterial resistance. If adverse reactions such as nausea, vomiting, or rash occur, discontinue the drug immediately and seek medical attention. The primary treatment for allergic rhinitis should focus on avoiding allergens and using standard anti-allergy medications. Roxithromycin should only be used short-term in specific cases with concurrent bacterial infection and should not be considered a routine treatment option.

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