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What are the SSRIs (selective serotonin reuptake inhibitors) used as antidepressants?

Nov 14, 2025 Source: Cainiu Health
Dr. Zhang Baohua
Introduction
Common SSRIs (selective serotonin reuptake inhibitors) generally include sertraline tablets, fluoxetine capsules, paroxetine tablets, fluvoxamine tablets, and citalopram tablets. Sertraline tablets: commonly used to treat conditions such as depression and obsessive-compulsive disorder, they work by inhibiting the reuptake of serotonin. After administration, it is important to monitor for gastrointestinal reactions such as nausea and diarrhea.

Commonly used SSRIs (selective serotonin reuptake inhibitors) for depression generally include sertraline tablets, fluoxetine capsules, paroxetine tablets, fluvoxamine tablets, and citalopram tablets. Detailed analysis is as follows:

1. Sertraline tablets: Commonly used to treat depression, obsessive-compulsive disorder (OCD), and other conditions. It works by inhibiting the reuptake of serotonin. After taking the medication, monitor for gastrointestinal side effects such as nausea and diarrhea. These symptoms usually gradually subside with continued use.

2. Fluoxetine capsules: Indicated for depression and panic disorder. The drug has a long duration of action. Initial use may cause side effects such as insomnia or anxiety. It should be started at a low dose under medical supervision, with gradual dose adjustments to reach an optimal level.

3. Paroxetine tablets: Used to treat depression, social anxiety disorder, and other conditions. It strongly inhibits serotonin reuptake. Some users may experience dizziness or drowsiness. When discontinuing the drug, dosage should be tapered gradually under a doctor's guidance to avoid withdrawal symptoms.

4. Fluvoxamine tablets: Primarily used for treating depression and OCD. It significantly affects liver metabolic enzymes. Inform your doctor before combining it with other medications to prevent potential drug interactions. Liver function should be monitored regularly during treatment.

5. Citalopram tablets: Suitable for various types of depression. It generally has good tolerability. Common side effects include dry mouth and increased sweating. Elderly patients or those with a history of heart disease should follow medical advice regarding dosage and undergo regular cardiac monitoring.

In daily life, SSRIs must be taken strictly according to medical instructions—do not adjust the dose or discontinue the medication on your own. If significant discomfort occurs during treatment, consult your doctor promptly.

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