Is it still possible to have an amniocentesis at 27 weeks of pregnancy?
Nov 14, 2025
Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, whether amniocentesis can be performed at 27 weeks of gestation should be determined based on the fetal condition, maternal health, and medical circumstances. Daily care includes maintaining external genital hygiene and wearing loose, breathable clothing. A balanced diet rich in protein and vitamins is recommended to enhance the body's immunity. Avoid strenuous exercise and abdominal trauma, and ensure adequate rest.
Generally speaking, whether amniocentesis can be performed at 27 weeks of gestation should be determined based on a comprehensive assessment of fetal condition, maternal health, and medical conditions. The specific analysis is as follows:
If screening tests such as maternal serum screening or non-invasive prenatal testing (NIPT) indicate abnormalities at 27 weeks of pregnancy, if ultrasound reveals possible structural issues in the fetus, and if the pregnant woman has no contraindications such as severe cardiopulmonary diseases or coagulation disorders, amniocentesis may be performed when the medical team evaluates that the benefits outweigh the risks. The procedure should be carried out by an experienced physician using precise equipment to minimize impact on both the fetus and the mother, thereby accurately assessing fetal health.
Amniocentesis should not be performed at 27 weeks if the fetus shows clear signs of intrauterine distress, if fetal position is abnormal and cannot be corrected, or if the pregnant woman has symptoms such as threatened miscarriage or pelvic inflammatory disease. Although fetal development is relatively stable at this stage, the procedure may trigger uterine contractions leading to miscarriage or increase the risk of intrauterine infection. Especially under inadequate medical conditions, these risks are difficult to control; therefore, safer alternative diagnostic methods should be prioritized.
In daily life, maintain good hygiene of the external genital area and wear loose, breathable clothing. Eat a balanced diet rich in protein and vitamins to enhance physical immunity. Avoid strenuous exercise and abdominal trauma, ensure adequate rest, and maintain emotional stability to prevent excessive anxiety. After undergoing amniocentesis, closely monitor for symptoms such as abdominal pain or vaginal bleeding, follow medical advice regarding bed rest, attend follow-up appointments as scheduled, and contact your doctor promptly if any abnormalities occur.
