What to do for fever in advanced liver cancer
Nov 14, 2025
Source: Cainiu Health
Dr. Ren Yi
Introduction
For fever in advanced liver cancer, the underlying cause should first be identified, followed by appropriate measures such as physical cooling, antipyretic medications, anti-infective treatment, controlling tumor progression, and improving the patient's overall condition; management should be standardized according to the individual patient's circumstances. If fever persists, body temperature exceeds 38.5℃, or chills occur, prompt medical attention is recommended. When temperature is below 38.5℃, wipe the forehead and other areas with lukewarm water.
For fever in advanced liver cancer, the underlying cause should first be identified, followed by measures such as physical cooling, antipyretic medications, anti-infective treatment, controlling tumor progression, and improving the patient's overall condition to relieve symptoms. Management should be standardized according to the individual patient’s condition. If fever persists, body temperature exceeds 38.5°C, or chills occur, prompt medical attention is recommended.
1. Physical cooling: When body temperature is below 38.5°C, use lukewarm water to wipe areas with major blood vessels—such as the forehead, neck, and armpits—or apply fever-reducing patches. Heat is dissipated through evaporation to help lower body temperature. Avoid using alcohol for sponge baths to prevent skin irritation.
2. Antipyretic medication: If body temperature exceeds 38.5°C or is accompanied by significant discomfort, antipyretics such as acetaminophen or ibuprofen may be used under medical guidance. Avoid self-administering aspirin, which may increase liver burden or raise the risk of bleeding.
3. Anti-infective treatment: If fever is caused by infection—such as pulmonary or biliary tract infection—sensitive antibiotics should be administered under medical supervision to control the infection source and alleviate fever. Liver function should be closely monitored during treatment.
4. Controlling tumor progression: For tumor-related fever, it is essential to control tumor growth through targeted therapy, interventional treatments, etc., reducing the release of pyrogenic substances from tumor cells and thereby addressing fever at its root.
5. Improving the patient's general condition: Provide nutritional support with adequate protein and vitamin intake to enhance immune resistance. Ensure sufficient fluid intake to prevent dehydration caused by fever and assist the body in coping with fever symptoms.
During fever, maintain indoor ventilation and a comfortable temperature and humidity level. Dress the patient in loose, breathable clothing and avoid excessive bundling. Encourage small, frequent sips of warm water, and provide a diet of light, easily digestible liquid or semi-liquid foods.
