Late-stage liver cancer with dementia symptoms discovered
Feb 03, 2024
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
In general, dementia-like symptoms observed in advanced liver cancer may be related to systemic inflammatory response, metabolic disturbances, side effects of chemotherapy and radiotherapy, hepatic encephalopathy, or brain metastasis of liver cancer, and targeted interventions are required. Liver cancer patients should maintain a light yet nutritious diet and follow a regular daily routine, which helps improve their quality of life.
In general, dementia-like symptoms observed in advanced liver cancer may be related to systemic inflammatory response, metabolic disturbances, side effects of chemotherapy and radiotherapy, hepatic encephalopathy, or brain metastasis of liver cancer, requiring targeted interventions. It is recommended to seek timely medical evaluation and treatment. Specific details are as follows:
1. Systemic Inflammatory Response
In advanced liver cancer, the growth and spread of cancer cells may trigger a systemic inflammatory response, releasing inflammatory mediators. These mediators can cross the blood-brain barrier and affect normal brain function, leading to impaired cognition and dementia-like symptoms. Cancer cell growth should be controlled with chemotherapy as advised by a physician.
2. Metabolic Disturbances
Liver cancer patients may experience systemic metabolic disturbances due to reduced appetite, weight loss, and other factors. This may deprive the brain of sufficient energy supply, impairing normal neuronal function and resulting in cognitive dysfunction and dementia. Patients should be provided with easily digestible, high-protein, high-calorie foods, preferably in small, frequent meals.
3. Side Effects of Chemotherapy and Radiotherapy
Patients with advanced liver cancer undergoing chemotherapy or radiotherapy may experience adverse effects on normal cells and tissues, including the central nervous system. These treatment-related side effects may lead to cognitive decline, including symptoms resembling dementia. Consult a physician to determine whether adjustments to treatment frequency or intensity are needed.
4. Hepatic Encephalopathy
Advanced liver cancer can severely impair liver function, leading to hepatic encephalopathy. This condition arises when liver insufficiency prevents effective metabolism and elimination of toxins, allowing them to accumulate in the body and disrupt brain function. This results in neurological abnormalities, including cognitive impairment, dementia, and difficulty concentrating. Treatment may include medications such as potassium magnesium aspartate injection, sodium glutamate injection, or ornithine aspartate for injection, as directed by a physician.
5. Brain Metastasis from Liver Cancer
In advanced stages, liver cancer cells may spread to the brain via the bloodstream or lymphatic system, forming brain metastases. These tumors can directly impair normal brain function, causing cognitive deficits and dementia. For small, solitary brain metastases, surgical removal may be performed under medical guidance. Radiotherapy may also be used in combination to slow tumor growth.
Patients with liver cancer should maintain a light yet nutritionally adequate diet and follow a regular daily routine to help improve quality of life.
