How are teratomas formed?
Nov 15, 2025
Source: Cainiu Health
Dr. Zhang Lu
Introduction
During embryonic development, primordial germ cells fail to differentiate normally, and residual immature cells undergo abnormal proliferation, gradually forming a teratoma containing various tissue components. Regular physical examinations are recommended to monitor changes in tumor size; if the tumor is small and asymptomatic, intervention may be deferred, but surgical removal is required upon enlargement. A family history of teratomas suggests the presence of inherited susceptibility genes in individuals, leading to abnormal regulation of germ cell development.
Teratoma formation may be caused by abnormal differentiation of embryonic germ cells, genetic factors, germ cell gene mutations, endocrine disorders, and other factors. If discomfort symptoms occur, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. Specific analyses are as follows:
1. Abnormal germ cell differentiation during embryogenesis: During embryonic development, primordial germ cells fail to differentiate normally. Residual immature cells undergo abnormal proliferation, gradually forming teratomas containing multiple tissue components. Regular physical examinations should be conducted to monitor changes in tumor size. Small, asymptomatic tumors may be observed without immediate intervention, while larger tumors require surgical removal.
2. Genetic influences: A family history of teratomas may indicate inherited susceptibility genes that disrupt the regulation of germ cell development, increasing the likelihood of teratoma formation. Emphasis should be placed on early screening; once a tumor is detected, prompt assessment and individualized treatment plans should be established.
3. Germ cell gene mutations: Gene mutations occurring during germ cell division can lead to uncontrolled cell proliferation and subsequent teratoma formation. These tumors often lack obvious early symptoms and are usually discovered incidentally during routine checkups. Small tumors should be monitored with regular follow-up exams, while larger tumors or those showing signs of malignant transformation require surgical excision and pathological examination. No special postoperative medication is typically needed.
4. Endocrine disorders: Hormonal imbalances in the body—such as abnormal fluctuations in estrogen and progesterone—can stimulate abnormal growth of germ cells, triggering teratoma development. Symptoms may include menstrual irregularities and breast tenderness. Under medical guidance, medications such as dydrogesterone tablets, estradiol valerate tablets, or progesterone capsules may be used to regulate hormone levels. Tumor size should be closely monitored, and surgery performed if necessary.
5. Environmental toxin exposure: Prolonged exposure to harmful substances such as chemical toxins or radiation can damage germ cells, leading to abnormal cell differentiation and teratoma formation. This may be accompanied by symptoms like fatigue and reduced immunity. It is important to avoid hazardous environments. As directed by a physician, supplements such as vitamin C tablets, vitamin E softgels, and compound vitamin B tablets may help improve cellular metabolism. Surgical removal should be performed promptly if the tumor increases in size.
In daily life, maintaining regular作息 and a balanced diet, while reducing intake of spicy and stimulating foods, is essential. Regular examinations of relevant body areas enable early detection and intervention, thereby lowering disease risk.
