What are the effects, benefits, and side effects of medroxyprogesterone acetate tablets?

Nov 15, 2025 Source: Cainiu Health

Dr. Zhang Lu

Introduction

Medroxyprogesterone acetate tablets, commonly referred to as hydroxyprogesterone acetate tablets, are used to regulate the menstrual cycle, prevent miscarriage and support fetal maintenance, treat endometriosis, assist in managing dysfunctional uterine bleeding, and alleviate dysmenorrhea. Possible side effects include gastrointestinal discomfort, endocrine disturbances, neurological symptoms, allergic reactions, and reproductive system abnormalities. These tablets should be used only under a doctor's supervision.

Medroxyprogesterone acetate tablets, commonly referred to as progestin tablets, have various functions and benefits including regulating the menstrual cycle, supporting pregnancy maintenance, treating endometriosis, assisting in the management of dysfunctional uterine bleeding, and alleviating dysmenorrhea. Potential side effects include gastrointestinal discomfort, endocrine disturbances, neurological symptoms, allergic reactions, and reproductive system abnormalities. These medications should be used only under medical supervision. If severe discomfort or unusual symptoms occur during treatment, prompt medical attention is recommended.

I. Functions and Benefits

1. Regulating the Menstrual Cycle: By supplementing progesterone, these tablets help regulate female endocrine rhythms, improving conditions such as irregular menstruation and amenorrhea. They assist in restoring regular menstrual cycles and are particularly suitable for menstrual disorders caused by progesterone deficiency.

2. Supporting Pregnancy Maintenance: In early pregnancy, insufficient progesterone levels may lead to threatened miscarriage. Supplementing with progesterone helps stabilize the pregnancy by inhibiting uterine contractions and reducing the risk of miscarriage. This use should only occur after a confirmed progesterone deficiency.

3. Treating Endometriosis: The medication suppresses endometrial proliferation and reduces the activity of ectopic endometrial tissue, thereby relieving symptoms such as dysmenorrhea and pelvic pain, and helping control disease progression.

4. Assisting in the Treatment of Dysfunctional Uterine Bleeding: It promotes complete shedding of the endometrium and reduces irregular bleeding. It is suitable for cases of non-organic (functional) uterine bleeding and helps restore normal uterine hemostatic function.

5. Alleviating Dysmenorrhea: It can relieve menstrual pain caused by progesterone deficiency or endometriosis by regulating endometrial secretion and reducing spasmodic uterine contractions during menstruation.

II. Side Effects

1. Gastrointestinal Discomfort: Common symptoms include nausea, vomiting, bloating, and loss of appetite. Some individuals may experience diarrhea or constipation. These are usually mild and may gradually subside with continued use.

2. Endocrine Disturbances: May cause changes in the menstrual cycle or abnormal menstrual flow. Some users may experience breast tenderness or weight gain, which are related to hormonal fluctuations induced by the drug.

3. Neurological Symptoms: Occasionally includes dizziness, headache, drowsiness, or insomnia. A few individuals may experience mood swings or irritability, though these typically do not interfere with continued use.

4. Allergic Reactions: Rarely, some people may develop itching, rashes, or redness. Severe allergic reactions are very uncommon. If any allergic symptoms appear, discontinue use immediately and seek medical treatment.

5. Reproductive System Abnormalities: Long-term or high-dose use may lead to endometrial atrophy or irregular vaginal bleeding. Dosage and duration must strictly follow medical instructions.

During treatment, take the medication at the same time each day to avoid missed doses, which could reduce effectiveness. Maintain a light and easily digestible diet, avoiding spicy or irritating foods. Regular monitoring of hormone levels is recommended to adjust the treatment plan according to clinical response. Do not alter the dosage or extend the treatment course without medical advice.

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What symptoms can occur with low progesterone levels?

In general, low progesterone levels may lead to symptoms such as menstrual irregularities, mood swings, dysmenorrhea, vaginal bleeding, and infertility. It is recommended to seek timely medical attention and, under the guidance of a qualified physician, use medications such as dydrogesterone tablets, progesterone capsules, or medroxyprogesterone acetate tablets. Additionally, maintaining adequate rest during treatment can aid in recovery.

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What medication is suitable for treating an endometrial thickness of 10mm?

Under normal circumstances, the endometrium refers to the lining of the uterus. An endometrial thickness of 10 mm may be related to factors such as the premenstrual period, early pregnancy, endometrial hyperplasia, endometritis, or polycystic ovary syndrome. It is recommended to seek timely medical attention, identify the underlying cause, and then follow the guidance of a qualified physician to use medications such as medroxyprogesterone acetate tablets, azithromycin dispersible tablets, metronidazole tablets, and progesterone capsules for treatment.

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Do you need progesterone supplementation in early pregnancy?

In general, whether progesterone supplementation is needed during early pregnancy depends on the specific progesterone level. If the progesterone level is less than 80 mmol/L, supplementation is usually required; if the level is greater than 80 mmol/L, supplementation is generally not necessary. Progesterone levels can be increased under medical guidance using oral medications such as dydrogesterone tablets, medroxyprogesterone acetate tablets, or progesterone capsules.

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口腔癌Patient吃What好

In general, oral cancer patients are advised to eat foods such as steamed pumpkin, fish paste, tofu pudding, apple puree, and lotus root starch. They may also take medications such as dexamethasone tablets, morphine hydrochloride sustained-release tablets, medroxyprogesterone acetate tablets, compound vitamin B tablets, and lactulose oral solution as directed by their physician to relieve discomfort. Additionally, maintaining good oral hygiene is important; patients should rinse their mouth with a mild mouthwash after meals and avoid consuming excessively cold foods.