What is the function of hyaluronidase?

　　Hyaluronidase generally functions to promote drug diffusion and absorption, assist in improving local edema, support tissue repair, enhance ocular drug penetration, and aid in improving local circulation. Detailed explanations are as follows:

　　1. Promote drug diffusion and absorption: Hyaluronidase can break down hyaluronic acid in tissues, reducing tissue viscosity and creating favorable conditions for drug diffusion. When used in conjunction with injections, it accelerates the local tissue penetration and absorption of drugs, reduces drug accumulation at the injection site, and enhances the speed of drug onset.

　　2. Assist in improving local edema: For local edema caused by trauma or inflammation, hyaluronidase promotes fluid movement and absorption within tissue spaces by degrading hyaluronic acid, thereby reducing tissue swelling and alleviating compression and discomfort associated with edema.

　　3. Support tissue repair: During wound healing, hyaluronidase helps regulate the local tissue microenvironment, facilitates the delivery of nutrients to the wound area, and aids in removing metabolic waste around the wound. This creates a favorable environment for cell proliferation and tissue regeneration, thus accelerating wound healing.

　　4. Enhance ocular drug penetration: In the treatment of eye diseases, pharmaceutical formulations containing hyaluronidase can reduce the barrier function of ocular surface tissues, promoting the penetration of active drug components through the cornea or conjunctiva. This increases drug concentration in ocular tissues and improves therapeutic efficacy.

　　5. Assist in improving local circulation: By enhancing tissue permeability, hyaluronidase promotes local blood circulation and increases tissue blood perfusion, delivering more oxygen and nutrients to the tissue and relieving local discomfort caused by poor circulation.

　　Hyaluronidase is an active pharmaceutical ingredient and must be used under professional guidance; self-administration without supervision is not recommended. Prior to use, potential allergic reactions should be evaluated. If symptoms such as redness, swelling, or itching occur after use, discontinue immediately and seek medical attention. Dosage and administration methods vary by application and must strictly follow established guidelines to ensure safety and effectiveness.