Does tandospirone citrate tablet cause dependence?

Nov 21, 2025 Source: Cainiu Health
Dr. Zhang Baohua
Introduction
Tandospirone citrate tablets generally have no obvious dependence. It belongs to non-benzodiazepine anti-anxiety drugs, with a mild mechanism of action that does not directly affect receptors associated with addiction. When used as directed, the risk of addiction is extremely low. If abnormal reactions occur during medication or symptoms rebound after discontinuation, medical advice should be sought promptly. The drug works by regulating serotonin receptors in the brain.

  Tandospirone citrate tablets generally do not cause significant dependence. As a non-benzodiazepine anti-anxiety medication, it has a mild mechanism of action and does not directly affect receptors associated with addiction. When used as prescribed, the risk of addiction is extremely low. If abnormal reactions occur during treatment or symptoms rebound after discontinuation, medical advice should be sought promptly.

  This medication exerts its anxiolytic effect by modulating serotonin receptors in the brain. Compared to benzodiazepines, it does not produce significant sedative or hypnotic effects, nor does it induce intense euphoria, making psychological dependence and physical addiction unlikely.

  In clinical use, as long as dosage adjustments and discontinuation are carried out gradually according to medical instructions, withdrawal symptoms generally do not occur. However, it is important not to stop the medication abruptly without consultation, as this may lead to worsening anxiety symptoms, which could be mistakenly interpreted as dependence. Proper discontinuation should always be conducted under a doctor's guidance with a gradual dose reduction.

  During treatment, the medication should be taken strictly as prescribed, avoiding unauthorized changes in dosage or discontinuation. Maintain regular sleep patterns and avoid alcohol and strong tea. Combining the medication with psychological counseling and moderate exercise can further improve anxiety symptoms and ensure safe use.

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