Is it good for autistic children to take lactulose?

Generally, autistic children with constipation and no contraindications can take lactulose as directed by a physician to help alleviate symptoms. If any abnormal reactions occur, prompt medical consultation is recommended. Detailed analysis is as follows:

Autistic children often have accompanying issues such as delayed intestinal development and impaired enteric nervous system development, making them prone to functional constipation. Lactulose, an osmotic laxative, helps regulate intestinal flora and acidifies the gut environment to stimulate peristalsis, thereby softening stools and relieving constipation. Lactulose increases bowel movement frequency in children with chronic constipation and improves stool consistency, providing adjunctive treatment for constipation caused by reduced intestinal motility in autistic children.

Lactulose is contraindicated in autistic children with galactosemia or hypersensitivity to its components. Additionally, long-term excessive use may cause side effects such as bloating, diarrhea, and electrolyte imbalances, and could potentially mask symptoms of organic diseases (e.g., Hirschsprung’s disease), leading to delayed diagnosis and treatment.

Prior to administration, a physician should evaluate the type and underlying cause of constipation and rule out organic diseases to determine the appropriate dosage. During treatment, closely monitor bowel movement frequency, stool characteristics, and the child's mental status. If persistent diarrhea or unusual irritability occurs, discontinue the medication immediately and seek medical reevaluation.