Will taking paliperidone extended-release tablets make you less talkative?

Nov 21, 2025 Source: Cainiu Health
Dr. Zhang Baohua
Introduction
Paliperidone extended-release tablets are antipsychotic medications primarily used to treat schizophrenia and related mood symptoms. Some patients may experience hallucinations, delusions, or disorganized thinking due to the illness itself, possibly accompanied by increased speech and loose associations. After taking the medication, as positive symptoms improve, patients may transition from a state of over-excitement to calmness, manifesting as reduced speech.

Generally, some individuals may experience reduced talking after taking paliperidone extended-release tablets, although this does not occur in everyone. If any abnormalities occur, it is recommended to seek medical attention promptly. Detailed analysis is as follows:

Paliperidone extended-release tablets are antipsychotic medications primarily used to treat schizophrenia and related emotional symptoms. Some patients may experience hallucinations, delusions, or disorganized thinking due to the illness itself, which can be accompanied by increased speech and loose associations. After taking the medication, as positive symptoms (such as hallucinations and delusions) improve, patients may transition from a state of over-excitement to calmness, resulting in decreased verbal output—this is considered one of the signs of effective treatment.

However, if a patient does not exhibit psychiatric symptoms, or develops worsening negative symptoms such as reticence, emotional blunting, or social withdrawal after starting the medication, this could be related to drug side effects or inappropriate dosage adjustment. In such cases, it is important to contact a physician promptly to evaluate whether the treatment plan needs modification.

Regular follow-up visits are necessary during treatment to monitor symptom changes and potential side effects. If severe adverse reactions such as difficulty swallowing, movement disorders, or seizures occur, the medication should be stopped immediately and medical help sought without delay.

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