What are the precautions for using povidone-iodine solution?
Povidone-iodine solution is a commonly used topical disinfectant. To ensure safe and effective use, it is essential to follow proper guidelines. Key precautions include identifying allergy contraindications, differentiating application sites, selecting appropriate concentrations, paying attention to special populations, and ensuring correct storage and usage. Specific details are as follows:

1. Identify Allergy Contraindications: The product is absolutely contraindicated in individuals allergic to iodine. If there is a known history of iodine allergy, this should be disclosed before use. Before first use, apply a small amount behind the ear or on the inner forearm and observe for 24 hours. If no reaction such as redness, swelling, or itching occurs, normal use may proceed. Discontinue immediately and rinse off any residual solution if signs of allergy appear.
2. Differentiate Application Sites: This solution is suitable for disinfection of skin and mucous membranes but must avoid sensitive areas. Do not apply to the eyes, deep oral cavity, or nasal mucosa. If accidental contact with the eyes occurs, immediately flush thoroughly with large amounts of water.
3. Select Appropriate Concentration: Use products with concentration suited to the specific situation. For minor skin wounds, a 1% concentration is appropriate; for large wound surfaces or mucosal disinfection, use a diluted concentration below 0.5%. Never arbitrarily increase the concentration, as higher levels may cause chemical burns to the skin or mucous membranes, leading to symptoms such as peeling and pain.
4. Pay Attention to Special Populations: Pregnant and breastfeeding women should use only under medical supervision, avoiding long-term or extensive application. Infants have delicate skin; the concentration should be halved, and use on broken skin should not exceed three consecutive days. Individuals with thyroid dysfunction should use cautiously to prevent iodine absorption from affecting their condition.
5. Proper Storage and Usage: Store the medication sealed and protected from light in a cool place out of children's reach, as high temperatures may reduce its effectiveness. Once opened, do not store for prolonged periods; it is generally recommended to use within one month.
This solution is for external use only and must never be ingested. If signs such as increased redness and swelling, exudation, or pus develop at the application site, discontinue use immediately and seek further medical treatment. Before routine use, carefully read the product instructions or consult a healthcare professional to clarify proper usage and avoid problems caused by improper application.