Which should be applied first, paeonol ointment or calamine lotion?

When the skin is red and has acne breakouts, it is generally recommended to apply calamine lotion first, followed by paeonol ointment. Calamine primarily helps astringe, relieve itching, and alleviate surface inflammation, while paeonol ointment focuses on anti-inflammatory action, skin repair, and deeper调理 (regulation). Using them in this sequence allows their effects to complement each other, achieving better recovery results. If redness and acne worsen after application, or if stinging, pain, or swelling occurs, medical advice should be sought promptly.

Calamine contains mainly calamine and zinc oxide, presenting as a suspension powder formulation. It has astringent, antipruritic, and protective effects on the skin. Applied first, it quickly dries surface secretions, relieves redness and itching, and creates a clean environment that facilitates the absorption of subsequent medications, without interfering with the penetration of paeonol ointment.

Paeonol ointment is an oily-based preparation containing paeonol, clove oil, and other ingredients, providing anti-inflammatory, anti-allergic, and skin-repairing benefits. When applied after the calamine has dried, it adheres better to the skin surface and can more effectively exert its anti-inflammatory effects. Applying the oily ointment first may prevent proper adherence of the calamine, reducing its astringent efficacy.

Before applying medication, cleanse the skin with a gentle facial cleanser and dry thoroughly. Shake the calamine well, then apply a thin layer and allow it to dry completely before applying the paeonol ointment. Use once or twice daily as directed by a physician, avoiding excessive application. Additionally, maintain good skin ventilation and reduce intake of spicy and high-sugar foods to support skin recovery.