What does it mean if a fleshy lump grows on the side of the scrotum, and what should be done about it?

Dec 03, 2025 Source: Cainiu Health

Dr. Liu Wenmin

Introduction

In general, a tumor growing on the scrotum may be caused by conditions such as skin soft fibroma, sebaceous gland hyperplasia, lipoma, genital warts (condyloma acuminata), or neurofibroma. Patients can choose appropriate treatments based on their specific situation. Daily care of the scrotal area is important; avoid scratching or squeezing the tumor. Wear loose clothing to reduce irritation.

Generally, a tumor growing on the scrotal area may be caused by conditions such as skin soft fibroma, sebaceous gland hyperplasia, lipoma, genital warts (condyloma acuminata), or neurofibroma. Patients can choose appropriate treatments based on their specific condition. Detailed analysis is as follows:

1. Skin Soft Fibroma

This results from benign proliferation of cutaneous connective tissue, often triggered by loose skin or friction irritation, presenting as soft, pedunculated, tumor-like protrusions. Avoid repeated friction; treatment options include cryotherapy or laser excision at a hospital.

2. Sebaceous Gland Hyperplasia

Caused by blockage of sebaceous ducts in the scrotal skin, leading to sebum accumulation and local tissue overgrowth, forming soft, tumor-like bumps. Maintain local cleanliness, wear breathable underwear, and reduce sebum secretion. Usually no special treatment is required.

3. Lipoma

Formed by benign aggregation of adipose cells, associated with abnormal fat metabolism, feeling soft and movable upon touch. Small lipomas can be monitored regularly, while larger ones or those affecting daily life may require surgical removal. Keep the wound dry after surgery.

4. Genital Warts (Condyloma Acuminata)

Caused by human papillomavirus (HPV) infection leading to abnormal epithelial cell proliferation, forming cauliflower-like or papillary tumors that bleed easily. Treatments include topical imiquimod cream or podophyllotoxin tincture as prescribed, oral transfer factor capsules, or electrocautery excision.

5. Neurofibroma

Develops from abnormal proliferation of nerve sheath tissue, usually firm in texture and often asymptomatic. Under medical guidance, patients may take vitamin B1 tablets or mecobalamin tablets. Larger tumors may require surgical removal, taking care to avoid damaging surrounding nerves.

Daily care of the scrotal area is important—avoid scratching or squeezing the tumor. Wear loose clothing to minimize irritation and keep the area clean and dry. Seek immediate medical attention if the tumor rapidly increases in size, hardens, or becomes painful for accurate diagnosis and treatment.

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