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What are the main functions of interferon-2b?

Dec 03, 2025 Source: Cainiu Health
Dr. Huang Yuhong
Introduction
Antiviral: Recombinant human interferon α2b can activate the host cell's antiviral mechanisms, inducing cells to produce antiviral proteins and enhancing cellular resistance to viral infection, thereby inhibiting replication and spread of various viruses. It is effective in treating viral infectious diseases such as acute and chronic viral hepatitis, herpes zoster, and genital warts.

Interferon α2b generally refers to recombinant human interferon α2b. Recombinant human interferon α2b typically possesses major functions including antiviral, immunomodulatory, antitumor, anti-inflammatory, and antifibrotic effects. The specific analysis is as follows:

1. Antiviral effect: Recombinant human interferon α2b can activate the host cell's antiviral mechanisms by inducing cells to produce antiviral proteins, thereby enhancing cellular resistance to viral infection. It suppresses the replication and spread of various viruses and is effective in treating viral infections such as acute and chronic viral hepatitis, herpes zoster, and genital warts.

2. Immunomodulation: This drug modulates the body's immune response by enhancing the activity of T and B cells, promoting antibody production, and activating macrophages and natural killer cells, thus increasing their ability to destroy pathogens and improving the body’s resistance against infections and tumors.

3. Antitumor effect: Recombinant human interferon α2b can inhibit tumor cell proliferation, promote apoptosis, and enhance the immune system's recognition and elimination of tumor cells. It serves as an adjunctive treatment for certain malignancies such as hairy cell leukemia, chronic myeloid leukemia, and non-Hodgkin's lymphoma.

4. Anti-inflammatory effect: Recombinant human interferon α2b inhibits the release of inflammatory mediators, reduces infiltration of inflammatory cells, alleviates inflammatory responses, and relieves local inflammatory symptoms such as redness, swelling, and pain. It is effective in treating inflammatory conditions like vaginitis and cervicitis.

5. Antifibrotic effect: In pathological conditions such as liver fibrosis and pulmonary fibrosis, recombinant human interferon α2b can inhibit fibroblast proliferation and collagen synthesis, reduce the development of fibrosis, and thus alleviate disease progression.

When using recombinant human interferon α2b, it is essential to strictly follow medical instructions and not self-administer the medication or adjust the dosage or duration of treatment without authorization.

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