Will taking too much paracetamol-pheniramine make you feel cold?

Dec 04, 2025 Source: Cainiu Health

Dr. Ren Yi

Introduction

If an excessive amount of paracetamol, chlorpheniramine, and artificial bezoar is taken, the chlorpheniramine component may intensify sedative effects, potentially impairing the body's temperature regulation function, causing vasoconstriction, and subsequently leading to chills, often accompanied by symptoms such as fatigue and dizziness. At this point, the drug concentration in the body is too high, exceeding the normal regulatory range, making abnormal physical reactions more likely to occur.

In general, taking too much acetaminophen-phenylpropanolamine-chlorpheniramine may cause chills. However, if the body's condition is stable or the overdose is minor, symptoms might not be obvious. If in doubt, it is recommended to seek medical advice promptly. Detailed analysis is as follows:

If a significantly excessive amount of acetaminophen-phenylpropanolamine-chlorpheniramine is taken, the chlorpheniramine component can intensify sedative effects, potentially impairing the body's temperature regulation function and causing blood vessel constriction, leading to chills. This is often accompanied by symptoms such as fatigue and dizziness. At this point, drug concentrations in the body are too high, exceeding normal regulatory capacity and easily triggering abnormal physical reactions.

If only a slight overdose occurs and the individual has good physical health and strong self-regulatory capacity, noticeable chills may not appear. With minor overdose, the impact of the medication on temperature regulation is limited, and the body can maintain normal function through its own regulatory mechanisms. Only mild side effects such as slight drowsiness may occur, without evident chills.

Acetaminophen-phenylpropanolamine-chlorpheniramine should be taken strictly according to the prescribed dosage; do not adjust the dose arbitrarily. If abnormal symptoms such as chills occur, discontinue the medication immediately and monitor body temperature. In cases of severe overdose or persistent symptoms, seek medical attention promptly for professional treatment.

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