Can the DTaP vaccine and the 13-valent pneumococcal vaccine be administered together?
Dec 08, 2025
Source: Cainiu Health
Dr. Zhou Xiaofeng
Introduction
Individuals with fever, acute illness, a history of severe allergy, or compromised immune function should postpone combined vaccination to avoid worsening symptoms or affecting vaccine response. Additionally, if an individual has previously experienced a serious adverse reaction after receiving any vaccine, they must inform the healthcare provider in advance for evaluation of whether simultaneous vaccination is appropriate.
Under normal circumstances, the DTaP vaccine and the 13-valent pneumococcal vaccine can be administered together. This co-administration complies with vaccination guidelines and is safe, although it should be postponed in cases of specific health conditions. If there are any concerns, it is recommended to consult the vaccination provider in advance. The detailed analysis is as follows:
The two vaccines target different diseases and their components do not interfere with each other. Administering them simultaneously does not reduce immune effectiveness nor increase the risk of severe adverse reactions. According to the vaccination schedule, children of certain age groups may receive both vaccines during the same clinical visit, which reduces the number of visits and improves vaccination convenience.
If the recipient has fever, an acute illness, a history of severe allergy, or compromised immune function, combined vaccination should be postponed to avoid worsening physical discomfort or impairing the immune response. Additionally, if a severe adverse reaction occurred after a previous dose of either vaccine, this should be reported to the healthcare provider for evaluation before considering simultaneous administration.
Prior to vaccination, inform the healthcare staff about the recipient’s current health status and vaccination history. After vaccination, remain at the site for 30 minutes of observation to monitor for any adverse reactions. Complete the full vaccination series as recommended to ensure adequate immune protection, and there is no need to overly concern about the safety of co-administration.
