Does an itchy throat affect the results of nucleic acid testing?

Itchy throat does not affect the results of nucleic acid testing. The core of nucleic acid testing is to detect whether the target pathogen's nucleic acid sequences are present in the sample. An itchy throat, usually caused by mucosal irritation or inflammation, does not alter the nucleic acid components in the sample or interfere with the testing process. If an itchy throat is accompanied by symptoms such as fever, cough, or worsening sore throat, medical evaluation should be sought promptly to identify the underlying cause.

Common causes of an itchy throat include allergies, dryness, and mild inflammation. These conditions affect only the surface of the respiratory mucosa and do not generate or destroy the nucleic acids of target pathogens such as the novel coronavirus. Nucleic acid tests use specific primers and probes that accurately identify target sequences, making them unaffected by localized mucosal discomfort. The accuracy of test results primarily depends on proper sampling techniques and sample storage conditions.

For daily care, maintain appropriate indoor humidity, drink plenty of warm water to soothe the throat, avoid loud talking and exposure to irritants such as dust and smoke, choose mild and easily digestible foods, and reduce intake of spicy or overly sweet foods. Gentle care measures can help relieve throat itchiness and support the health of the respiratory mucosa.