Can I receive the COVID-19 vaccine 16 years after undergoing mitral valve replacement?

Dec 09, 2025 Source: Cainiu Health
Dr. Tian Hongbo
Introduction
However, if cardiac function has not yet fully recovered, or if symptoms such as chest tightness, shortness of breath, and fatigue are present, vaccination may increase the burden on the heart and trigger adverse reactions. In addition, vaccination should be postponed during acute illnesses such as colds or fever, or in cases of allergy to vaccine components, with priority given to managing the underlying condition or avoiding allergic risks.

Generally, patients who have undergone mitral valve replacement and have remained stable for 16 years may receive the COVID-19 vaccine. However, vaccination should be postponed if heart failure or acute symptoms are present. If in doubt, a comprehensive evaluation is recommended before making a decision. Detailed analysis is as follows:

If, after 16 years post-surgery, cardiac function is normal, there are no significant discomforts, and daily activities are unrestricted, receiving the COVID-19 vaccine will not impose additional strain on the heart. The immune response in these individuals is generally comparable to that of the general population, and vaccination can effectively reduce the risk of infection, meeting the basic criteria for immunization.

However, if cardiac function has not fully recovered, or if symptoms such as chest tightness, shortness of breath, or fatigue are present, vaccination might increase the burden on the heart and potentially trigger adverse reactions. Additionally, vaccination should be delayed during acute illnesses such as colds or fever, or if there is known allergy to any vaccine component, with priority given to managing the underlying condition or avoiding allergic risks.

Prior to vaccination, patients should inform their doctor about their surgical history, current cardiac function, and medication use. Should persistent discomfort occur, prompt medical consultation and reporting are necessary for timely management.

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