What is myelofibrosis
Dec 12, 2025
Source: Cainiu Health
Dr. Li Feng
Introduction
In general, myelofibrosis is a rare, chronic progressive blood disorder and belongs to the group of myeloproliferative diseases. Stabilizing the condition requires attention to daily details. In terms of diet, consume more foods rich in iron and vitamins to help improve anemia, while maintaining balanced nutrition. Ensure adequate rest, avoid staying up late and heavy physical labor to reduce physical strain.
Generally, myelofibrosis is a rare and chronically progressive blood disorder, classified as a type of myeloproliferative neoplasm. A detailed analysis is as follows:
Myelofibrosis is a disease in which the bone marrow's hematopoietic tissue is replaced by fibrous tissue, leading to impaired blood cell production. Abnormal activation of hematopoietic stem cells in the bone marrow triggers excessive proliferation of fibrous tissue, which compresses the normal space for blood formation, resulting in reduced production of red blood cells, white blood cells, and platelets. In some patients, the liver and spleen may take over blood cell production (extramedullary hematopoiesis), leading to symptoms such as anemia, splenomegaly, fatigue, and bleeding, significantly disrupting normal physiological functions.
Stabilizing the condition requires attention to daily lifestyle details. Diet should include iron-rich and vitamin-rich foods to help improve anemia, while maintaining overall nutritional balance. Ensure adequate rest, avoid staying up late and heavy physical labor to reduce bodily strain. Keep indoor areas well-ventilated, regularly clean and disinfect, and adjust clothing promptly with changing weather to lower the risk of infection. Engage in gentle physical activities such as walking to strengthen the body, but avoid overexertion, and seek medical attention promptly if any discomfort occurs.
